It is a pain-relieving medicine that helps in treating moderate to severe pain.
It is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Pain- Pain signals the nervous system that something may be wrong, and can be sharp or dull, coming or going. It can be experienced in one area or all over. There are two types of pain: acute and chronic. Acute pain, sudden and often treated, can go away, while chronic pain can last for years and cause severe problems.
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Dolonip is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
No. Dolonip should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.
No. Dolonip is not a medication to control hypertension. It is important to note that Dolonip decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Dolonip.
No. Dolonip should not be used with diuretics. Dolonip reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
No. Dolonip should not be combined with Losartan. It is important to note that Dolonip decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dolonip.
No. Dolonip should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
No. Dolonip should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Both Dolonip and nimesulide are pain killers. However, Dolonip is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
No. Dolonip should not be used with lithium. Dolonip leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Yes. Dolonip can be given for the treatment of acute gout. Research studies have shown Dolonip to be highly effective in the treatment of acute gout.
Both Dolonip and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Dolonip. Ketoprofen gel also showed excellent tolerability.
Yes. Dolonip can be combined with beta-cyclodextrin. Research has shown that combining Dolonip with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
No. Dolonip should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dolonip.
No. Dolonip and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Yes. Dolonip is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Dolonip in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Dolonip so taking piroxicam can lead to increased risk of renal failure by many folds.
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
No. Dolonip is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Dolonip as the cause of back pain can be different for different person.
Both Dolonip and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Dolonip.
Yes. Dolonip can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Yes. Methocarbamol can be used with Dolonip as no serious side effects are known. Inform your doctor before starting any of the medication.
Yes. There are alternatives to Dolonip. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
No. Dolonip is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
No. Dolonip is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Both Dolonip and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Dolonip.
Both Dolonip and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Dolonip.
Dolonip is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Yes. Dolonip can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
No. Dolonip should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Yes. Dolonip is a non-steroidal anti-inflammatory drug (NSAID).
Dolonip is a sulphur containing compound. Dolonip can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Dolonip is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
No. Dolonip is contraindicated in cases of active peptic ulcer disease. Dolonip is known to cause gastric ulceration and bleeding.
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Yes. Paracetamol can be used with Dolonip as no serious side effects are known. Inform your doctor before starting any of the medication.
Dolonip is not approved for the treatment of migraine. Research studies have shown that Dolonip is effective in significantly decreasing the pain associated with migraine without aura.
Yes. You can donate blood when on Dolonip. Do inform your doctor before donating blood.
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Dolonip or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Dolonip.
No. Dolonip is not a drug to treat allergy. It is a pain killer.
Yes, Dolonip can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
No. Dolonip is not known to cause high. It is a non-narcotic painkiller.
MBA in Pharmaceutical
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Create ABHACaution is advised when consuming alcohol with this drug.
It should be used cautiously in patients with severe kidney disease.
The drug should be used with caution in patients with liver disease.
It is unsafe to use during pregnancy as it may pose risk to the developing baby.
It is considered to be safe to use during breastfeeding.
It may decrease alertness, affect your vision or make you feel sleepy and dizzy.