Yes, Phosmid can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Phosmid for nephrotic syndrome has not been established.

Yes, Phosmid is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Yes, Phosmid may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Phosmid is high in the urinary bladder. Other rare cancers that may occur with use of Phosmid include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

No, there is no evidence that you need to avoid sun exposure while on Phosmid. Skin and nail discoloration are reported rarely with Phosmid.

Yes, Phosmid can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Phosmid.