This medicine is a combination of three antidiabetic medicines: Glibenclamide, Pioglitazone, and Metformin. These three drugs work by different mechanisms and collectively control the blood sugar level when no single or dual therapy could show any effect. Glibenclamide is a sulfonylurea which shows its activity by increasing the amount of insulin released from the pancreas and reducing the glucose level in the blood. Metformin is a biguanide, it reduces glucose production in the liver, delays glucose absorption from the intestine and makes the body sensitive to insulin. Pioglitazone is a thiazolidinedione that also increases insulin sensitivity.

• Use this medicine as per the advice given by your health care provider
• The medicine should be swallowed whole with a glass of water, without breaking and crushing it
• The medicine should be taken with food

• Take as prescribed by your doctor, usually with meals
• Monitor blood sugar levels regularly
• Inform your doctor if you have kidney or liver problems

• Beneficial in treating blood sugar level in diabetic adults

• Diarrhea
• Sinus infection
• Nausea
• Loss of appetite
• Headache
• Erectile dysfunction
• Vision disorder
• Blood in urine
• Weight gain