
Zonamax ES 1000 mg/500 mg Injection
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Zonamax-ES 1000/500 mg Injection 10ml is a powerful combination antibiotic used to treat severe bacterial infections. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg), making it highly effective against a wide range of bacterial strains, including resistant ones.
This injectable formulation is often used in hospitals to manage serious infections like pneumonia, urinary tract infections (UTIs), skin infections, intra-abdominal infections, and sepsis. It works quickly and efficiently under medical supervision, ensuring optimal recovery.
Ceftriaxone, a third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, ultimately killing the bacteria. Sulbactam: A beta-lactamase inhibitor that enhances the effectiveness of Ceftriaxone by preventing bacteria from breaking down the antibiotic. Together, these components make Zonamax-ES Injection highly effective against resistant bacterial infections.
- Administered by a healthcare professional through an intravenous (IV) infusion or intramuscular (IM) injection.
- Dosage and duration depend on the severity and type of infection.
- Do not self-administer this injection. Follow the doctor’s instructions closely for best results.
- Do not use if allergic to Ceftriaxone, Sulbactam, or other cephalosporins.
- Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be required.
- Not recommended for premature babies or neonates with jaundice.
- Broad-spectrum antibiotic targeting both Gram-positive and Gram-negative bacteria.
- Effective in treating severe and life-threatening bacterial infections.
- It reduces bacterial resistance.
- Diarrhea
- Itching
- Decreased hemoglobin
- Decreased hematocrit level
- Positive Coombs test
- Low blood platelets
- Injection site phlebitis
- Increased aspartate aminotransferase
- In case you miss your injection appointment, reach out to your doctor immediately for guidance.
- Following their instructions is essential to maintain the continuity and effective management of your treatment plan.
Health And Lifestyle
- Diuretic (Furosemide)
- Anticoagulants (Warfarin)
- Other Antibiotics (Gentamicin)
- Cefoperazone+Sulbactam shows no known interactions with food, simplifying its usage without specific dietary restrictions.
- Consult your healthcare provider for more information

Bacterial infections are illnesses caused by harmful bacteria that multiply or release toxins in the body. They can affect different parts of the body, such as the skin, lungs, gut, blood, or brain. They can cause symptoms such as fever, chills, pain, swelling, rash, or organ dysfunction.
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- ಸುರಕ್ಷಿತ
Ingesting alcohol with medicine may induce a Disulfiram reaction, causing symptoms like flushing, increased heart rate, nausea, and low blood pressure.
Medicine is generally safe in pregnancy while animal studies show minimal adverse effects, consult your doctor for personalized advice.
Considered safe during breastfeeding; limited transfer to breast milk; extended use may lead to potential side effects like rash and diarrhea.
Limited information on medicine in kidney disease consult your doctor for personalized guidance.
Limited data on medicine in liver disease; consult your doctor for advice and potential adjustments in dosage.
Does not affect the driving ability.
- Complete the full course of antibiotics to prevent resistance.
- Avoid self-medicating with antibiotics for minor ailments.
- Monitor for signs of worsening infections and seek immediate care if needed.
- Category: Combination antibiotic (Ceftriaxone + Sulbactam)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Prescription Required: Yes
- Formulation: Injectable solution (IV/IM)
- Store at a temperature below 30°C.
- Keep away from direct sunlight and moisture.
- Use reconstituted solution immediately to avoid contamination.
- Dosage depends on the infection type and severity.
- Typical adult dosage: 1–2 g daily, divided into one or two doses.
- Pediatric dosage: Adjusted based on body weight, as prescribed by the doctor.
Zonamax-ES 1000/500 mg Injection 10ml is a trusted combination antibiotic for severe bacterial infections. With its potent formula of Ceftriaxone and Sulbactam, it combats resistant bacteria effectively, ensuring rapid recovery under medical supervision.

