Introduction to Degrain 10mg/325mg Tablet

Degrain 10mg/325mg Tablet fall into the category of medicines employed for alleviating migraines. It integrates a prokinetic substance and an analgesic to handle nausea and discomfort associated with migraines.

Domperidone influences the brain's anti-emetic center, improving stomach and intestinal movement to prevent nausea and vomiting caused by migraines. Paracetamol/Acetaminophen, functioning as an analgesic and antipyretic, prohibits the discharge of the pain and fever triggers related to migraines. As a combined treatment, they deliver a comprehensive strategy to lessen migraine symptoms.

To achieve maximal benefits, comply with your physician's instruction regarding the prescribed quantity and duration. This compound comes in various formats, like tablets and liquid solutions. The tablet needs to be ingested as a whole, and for the liquid form, accurate measurement should be taken using the provided device. It can be consumed with or without meals, but consistent timing is suggested for improved outcomes.

Frequent side effects of this dual treatment encompass dry mouth, chest discomfort, light-headedness, syncope, extreme fatigue, skin eruption, and breast discomfort and sensitivity.

Association has been found between Plamol-D and higher risks of severe ventricular arrhythmias, inclusive of potentially fatal ones like torsades de pointes. Lowest effective dose for the shortest duration is suggested, especially for those with pre-existing cardiac conditions or on medicines prolonging the QT interval. Both Domperidone and Paracetamol get metabolized in the liver, calling for regular liver function checks, particularly for individuals with underlying liver conditions. Paracetamol, notably, carries a risk of liver damage if excessively consumed, thus necessitating caution when taking it with other liver-metabolising drugs.

In case a dose is forgotten, ingest it as soon as remembered. But if the time for the next dose is near, skipping the previous one is advised to follow the regular medicinal routine. Double doses should be evaded. Seeking medical advice is vital for effectively managing overlooked doses.

How Degrain 10mg/325mg Tablet Works?

The Degrain 10mg/325mg Tablet influences the brain's vomit control hub to reduce stomach and intestinal activity, mitigating nausea and vomiting associated with migraines. Paracetamol, a painkiller and fever suppressant, inhibits the discharge of chemical agents that trigger pain and fever connected to migraines. Combined, they alleviate the symptoms of migraines.

How To Use Degrain 10mg/325mg Tablet

  • Adhere to your physician's instructions on its application.
  • This is accessible in various compositions, such as pills and liquid mixtures.
  • Ingest the capsule completely and evaluate the fluid medication with the supplemented instrument.
  • Though you can consume this with or without meals, it is suggested to ingest this treatment at a fixed moment for improved outcomes.

Special Precautions About Degrain 10mg/325mg Tablet

  • Domperidone has been associated with an increased risk of serious ventricular arrhythmias (irregular heartbeats), including torsades de pointes, a potentially life threatening arrhythmia. It is advised to use the lowest effective dose for the shortest duration, especially in individuals with preexisting heart conditions or those taking medications that prolong the QT interval.
  • Both domperidone and paracetamol are metabolized in the liver. Regular monitoring of liver function may be recommended, especially in individuals with preexisting liver conditions Paracetamol, in particular, is associated with the risk of liver damage if taken in excessive amounts, and combining it with other medications metabolized by the liver may warrant caution.

Benefits Of Degrain 10mg/325mg Tablet

  • Eases nausea and vomiting.
  • Relieves pain and fever.
  • Prevents and reduces migraine frequency.
  • It Blocks chemicals causing nausea.

Side Effects Of Degrain 10mg/325mg Tablet

  • Dry mouth
  • Chest pain
  • Dizziness and fainting
  • Extreme tiredness
  • Skin rash
  • Breast pain and tenderness

What If I Missed A Dose Of Degrain 10mg/325mg Tablet

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

FAQS

Degrain 10mg/325mg Tablet

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Degrain can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Degrain 10mg/325mg Tablet

Q. Can I get addicted to Degrain?

No, there is no report of any patient getting addicted to Degrain.

Degrain 10mg/325mg Tablet

Q. What is the recommended storage condition for the Degrain?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Degrain 10mg/325mg Tablet

Q. What is Degrain?

Degrain is a combination of two medicines: Domperidone and Paracetamol / Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol / Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

Degrain 10mg/325mg Tablet

Q. Can the use of Degrain cause damage to liver?

Yes, Degrain can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.

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Safety Advice For Degrain 10mg/325mg Tablet

check for risk indication explain below.

  • High risk
  • Moderate risk
  • Safe

Alcohol

Be careful when drinking alcohol with medicine because it might intensify side effects.

Pregnancy

The medicine might be hazardous during pregnancy. Before usage, have a discussion with your doctor about possible benefits and risks.

Breast feeding

Regarded as safe while breastfeeding; research indicates little drug transition to breast milk, thus posing minimal risk to the infant.

Kidney

Administer medicine with care in case of kidney disease; refer to your doctor for possible dosage alterations and observation.

Liver

Be cautious in case of liver disease as dosage modification might be required. Severe liver disease requires avoiding the medicine.

Alcohol

Be careful when drinking alcohol with medicine because it might intensify side effects.

Pregnancy

The medicine might be hazardous during pregnancy. Before usage, have a discussion with your doctor about possible benefits and risks.

Breast feeding

Regarded as safe while breastfeeding; research indicates little drug transition to breast milk, thus posing minimal risk to the infant.

Kidney

Administer medicine with care in case of kidney disease; refer to your doctor for possible dosage alterations and observation.

Liver

Be cautious in case of liver disease as dosage modification might be required. Severe liver disease requires avoiding the medicine.

Disease Explanation

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A migraine is a type of headache that causes severe throbbing or pulsing pain, usually on one side of the head. It can also cause nausea, vomiting, and sensitivity to light and sound. Migraines can be triggered by various factors, such as stress, food, hormones, or weather.

Update on: Monday, 22 January, 2024

Written By:

Written By:

Salman Khan