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Introduction to Erbitux 100mg Infusion
Erbitux 100mg Infusion is a targeted cancer therapy used to treat colorectal cancer and head & neck cancer. It contains Cetuximab (100mg), a monoclonal antibody that blocks epidermal growth factor receptor (EGFR), preventing cancer cell growth. It is administered as an intravenous (IV) infusion under medical supervision.
Safety Advice for Erbitux 100mg Infusion
- High risk
- Moderate risk
- Safe
Consult your doctor about consuming alcohol with this drug.
Consult your doctor, as it may be unsafe during pregnancy due to potential harm to the baby.
Erbitux 100mg Infusion is likely unsafe for breastfeeding mothers, as it may pass into breastmilk and harm the baby.
Be cautious, as it may cause side effects that affect your ability to drive.
Generally safe, but consult your doctor if you have kidney disease.
Limited information available, so consult your doctor if you have liver disease.
How Erbitux 100mg Infusion works
Erbitux 100mg Infusion is a monoclonal antibody that specifically binds to receptors on cancer cells. Thus it flags the cancer cells for destruction by the bodys immune system. Targets and binds to EGFR (epidermal growth factor receptor) on cancer cells. Prevents tumor growth by blocking signals that promote cell division. Enhances the effectiveness of chemotherapy and radiation therapy in certain cancers.
How To Use Erbitux 100mg Infusion
- Administration: Given as an intravenous (IV) infusion by a healthcare professional. First dose is infused over 2 hours, followed by weekly infusions over 1 hour.
- Dosage: Colorectal Cancer: Usually given in combination with chemotherapy. Head & Neck Cancer: Given along with radiotherapy or chemotherapy.
- Duration: Erbitux 100mg Infusion Continued until disease progression or unacceptable toxicity occurs.
Special Precautions About Erbitux 100mg Infusion
- May cause severe allergic reactions—patients are monitored closely during infusion.
- Erbitux 100mg Infusion use with caution in heart disease, as it may cause arrhythmias. Regular skin care is required, as it may cause severe acne-like rash
- Avoid sun exposure, as Cetuximab increases skin sensitivity.
- Inform your doctor if you have lung disease, as it may worsen respiratory conditions.
Benefits Of Erbitux 100mg Infusion
- Slows tumor growth in EGFR-positive colorectal and head & neck cancers.
- Improves survival rates when used with chemotherapy or radiation.
- Erbitux targets only cancer cells, reducing damage to normal cells compared to traditional chemotherapy.
- May allow surgery in previously inoperable tumors by shrinking them.
Side Effects Of Erbitux 100mg Infusion
- Common Side Effects: Skin rash, dry skin, nausea, vomiting, diarrhea, low magnesium levels.
- Serious Side Effects: Severe allergic reactions, difficulty breathing, heart problems, lung infections.
What If I Missed A Dose Of Erbitux 100mg Infusion
- Inform your doctor immediately if you miss an infusion appointment.
- Do not self-administer the medication.
Health And Lifestyle
Use sunscreen and moisturizers to prevent skin irritation and rashes. Drink plenty of fluids to avoid dehydration. Maintain a healthy diet to support immunity and manage side effects. Avoid smoking and alcohol, as they may worsen side effects. Report any unusual side effects like rash, difficulty breathing, or irregular heartbeat immediately.
Drug Interaction
- Chemotherapy Drugs (e.g., Irinotecan, 5-Fluorouracil) – May enhance side effects.
- Blood Pressure Medications (e.g., Amlodipine, Metoprolol) – May cause heart complications.
- Electrolyte-Lowering Drugs (e.g., Diuretics, Corticosteroids) – May worsen low magnesium levels.
Disease Explanation
Colorectal Cancer – Cancer of the large intestine or rectum, often associated with EGFR overexpression. Head & Neck Cancer – Includes cancers of the mouth, throat, and larynx, often treated with radiation. EGFR-Positive Tumors – Cancers that overproduce the epidermal growth factor receptor (EGFR), leading to uncontrolled growth.
Tips of Erbitux 100mg Infusion
Use sun protection, as Cetuximab increases skin sensitivity.,Stay hydrated to manage diarrhea and prevent dehydration.,Attend regular follow-ups to monitor blood counts and electrolyte levels.
FactBox of Erbitux 100mg Infusion
- Manufacturer: Merck Ltd
- Composition: Cetuximab (100mg)
- Class: Monoclonal Antibody (EGFR Inhibitor)
- Uses: Treatment of Colorectal Cancer, Head & Neck Cancer
- Prescription: Required
- Storage: Store in a refrigerator (2-8°C), do not freeze
Storage of Erbitux 100mg Infusion
- Keep refrigerated (2-8°C), do not freeze.
- Store in original packaging to protect from light.
- Do not shake or mix before use.
Dosage of Erbitux 100mg Infusion
Colorectal Cancer: Initial dose of 400mg/m², followed by 250mg/m² weekly.,Head & Neck Cancer: Initial dose 400mg/m², then 250mg/m² weekly with radiation.
Synopsis of Erbitux 100mg Infusion
Erbitux 100mg Infusion is a targeted cancer therapy that blocks EGFR, slowing the growth of colorectal and head & neck cancers. It is given intravenously and works best when combined with chemotherapy or radiation.
FAQ's on Erbitux 100mg Infusion
Is Erbitux cytotoxic agent or vesicant or radiosensitizer?
It is not a radiosensitizer, but usually used in combination with radiotherapy to treat the cancers. It is not a vesicant (irritant)
Is Erbitux a chemotherapy drug?
Erbitux is a cytotoxic drug that is used in the chemotherapy of cancers of colon and rectum, and head-neck cancers
Does Erbitux cause hair loss?
Yes. Erbitux is a chemotherapy agent, which may cause hair loss. Please consult your doctor if you experience such side effect
Is Erbitux US FDA approved?
Yes, Erbitux is approved by US FDA in 2009 to treat certain type of cancer of colon, rectum and head-neck cancer
How long does the rash last?
The duration of skin rash depends upon its type and severity. Please consult your doctor for advice.
How is Erbitux administered?
Erbitux is generally administered by intravenous (IV infusion) route, with or without radiotherapy
Why does Erbitux cause a rash?
Erbitux may cause rashes
How long does Erbitux take to work?
It starts working within weeks, but full benefits may take several months.
Can Erbitux be used alone for cancer treatment?
It is usually combined with chemotherapy or radiation for better results.
Does Erbitux cure cancer?
No, but it slows tumor growth and prolongs survival in advanced cancers.
What should I do if I develop a skin rash while on Erbitux?
Use moisturizers, mild soaps, and sunscreen. Inform your doctor if the rash is severe.
Does Erbitux cause hair loss?
No, it does not typically cause hair loss like chemotherapy.
Can Erbitux be used in all colorectal cancer patients?
No, it is only effective in EGFR-positive, RAS wild-type colorectal cancer.
Is Erbitux safe for elderly patients?
Yes, but elderly patients may have a higher risk of side effects like heart issues.
Can I receive Erbitux if I have lung disease?
Use with caution, as it may cause lung infections or breathing problems.
How is Erbitux different from chemotherapy?
Erbitux targets specific cancer cells, while chemotherapy affects both cancerous and normal cells.
Can pregnant women take Erbitux?
No, it is not recommended during pregnancy due to potential harm to the baby.
Written By
Salony Priya
MBA in pharmaceutical management
Content Updated on
Saturday, 8 Feburary, 2025Prescription Required
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