Researchers have suggested that exposure to toxins during warfare, or strenuous physical activity, are possible reasons for why some veterans and athletes may be at increased risk of developing ALS.

The early symptoms of ALS include muscle twitches in the arm, leg, shoulder, or tongue, muscle cramps, tight and stiff muscles (spasticity), muscle weakness affecting an arm, a leg, neck or diaphragm, slurred and nasal speech and difficulty in chewing or swallowing. For many individuals the first sign of ALS may appear in the hand or arm as they experience difficulty with simple tasks such as buttoning a shirt, writing, or turning a key in a lock. In other cases, symptoms initially affect one of the legs, and people experience awkwardness when walking or running or they notice that they are tripping or stumbling more often.

There are no studies to support if ALS can be prevented or not. However, one can reduce the possibility of acquiring the disease by knowing various risk factors. The risk factors associated with ALS include smoking and exposure to pesticides and insecticides. In addition to that, another report suggests that people who have served in the military can also have high risks of developing ALS.

The most common side effects of Fraseda include confusion, headache, and difficulty in walking. Other uncommon side effects are skin allergy (rash and itching), breathing difficulty, chest tightness, wheezing, coughing (especially in people with asthma), and fungal infections.

Inform your doctor or pharmacist if you are allergic to edaravone, any other medications, sodium bisulfite, or any of the ingredients in Fraseda injection. If you are taking or planning to take any other prescription and nonprescription medications, vitamins, and nutritional supplements inform your doctor beforehand. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Tell your doctor if you have or have ever had asthma or if you are pregnant or planning to conceive, or are breastfeeding. If you become pregnant while receiving edaravone, call your doctor.

Fraseda injection comes as a solution (liquid) to be injected intravenously (into a vein) over 60 minutes by a health care professional in a doctors office or medical facility. During the initial stage of treatment, Fraseda is usually given once a day for the first 14 days of a 28-day cycle. After the first cycle, it is given once a day for the first 10 days of a 28-day cycle. Your doctor will decide how often you are to receive Fraseda based on your bodys response to this medication.

Caucasians and non-Hispanics are most likely to develop the disease. About 5 to 10 percent of all ALS cases are familial, which means that an individual inherits the disease from his or her parents. ALS can strike at any age, symptoms most commonly develop between the ages of 55 and 75. It is slightly more likely to develop in men than in women. However, as we age the difference between men and women disappears. Furthermore, some studies suggest that military veterans are about 1.5 to 2 times more likely to develop ALS because of toxin exposure during warfare.

Fraseda injection is used to treat amyotrophic lateral sclerosis (ALS). ALS is a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken. Fraseda works by slowing the nerve damage associated with the worsening of ALS symptoms.