Introduction to Glemin PM 2mg/500mg/15mg Tablet

Glemin PM 2mg/500mg/15mg Tablet is a prescribed medication used for the treatment of chronic type 2 diabetes. It contains a mix of three specific drugs: Glimepiride, Metformin, and Pioglitazone.

Each component aids in the regulation of diabetes in unique ways.

Glimepiride: Classed as sulfonylurea, it stimulates the pancreas to release insulin and aids in reducing blood sugar levels by boosting the insulin production of the body.

Metformin: This biguanide enhances insulin response, lessens the glucose production by the liver, and strengthens the body's response to insulin. It is also instrumental in lowering blood sugar levels.

Pioglitazone: As a thiazolidinedione, it aids in strengthening insulin sensitivity within the body's cells, which in turn leads to better insulin response. This results in reduced blood sugar levels accordingly.

Please adhere to the dosage directions provided by your medical practitioner. This drug tends to come in a fixed combination dosage, and the quantity of tablets to be consumed may vary.

Usually, this medication is taken alongside meals to mitigate the risk of gastrointestinal distress. 

Common adverse effects of this medication include the possibility of hypoglycemia which includes shakiness, dizziness, excess sweating, and confusion. Digestive disorders like nausea, diarrhea or abdominal discomfort can also occur. Additionally, weight fluctuations may be observed in some cases.

Owing to potential implications on the kidneys, those administered Metformin may require regular kidney efficiency tests. Similarly, due to risks related to the liver, periodic liver efficiency tests might be advised.

If you forget to take a dose, act immediately. Take the forgotten dose as soon as you recollect, unless the next dosage time is near. In such a scenario, it is recommended to skip the forgotten dose to avoid overdosage.

How Glemin PM 2mg/500mg/15mg Tablet Works?

Glimepiride, an insulin-secretagogue, promotes insulin discharge from the pancreatic glands, assisting in lowering blood sugar levels. Metformin, an anti-hyperglycemic agent, reduces liver glucose production and boosts peripheral insulin receptivity. Pioglitazone, an insulin sensitizer, betters insulin responsiveness in fat tissue and skeletal muscle system. Collectively, these drugs interact synergistically to control insulin discharge, diminish liver glucose secretion, and increase peripheral glucose use. This drug mix offers a successful tactic for treating diabetes by tackling various aspects of sugar balance.

How To Use Glemin PM 2mg/500mg/15mg Tablet

  • Heed your physicians' advice for this medication, consuming it in the specified amount and time period.
  • You can ingest this medication with or without meals, but keeping a uniform time every day is advised for optimal effects.
  • Ingest the pill whole; refrain from chewing, fragmenting, or rupturing it.

Special Precautions About Glemin PM 2mg/500mg/15mg Tablet

  • Glimepiride increases insulin release, which can lead to hypoglycaemia (low blood sugar). The risk of hypoglycaemia is higher with higher doses of glimepiride. Patients should be educated about recognizing the signs and symptoms of hypoglycaemia and should closely monitor their blood sugar levels. Dosage adjustments or changes in diet may be necessary to manage hypoglycaemia.
  • Glimepiride is primarily eliminated through the kidneys. In patients with impaired renal function, the drug may accumulate, increasing the risk of hypoglycaemia. Regular monitoring of renal function is recommended, and dosage adjustments may be necessary in individuals with significant renal impairment.
  • Metformin is known to cause gastrointestinal side effects, including nausea, vomiting, and diarrhoea. Combining it with glimepiride may increase the likelihood of these effects. Informing healthcare providers about any persistent or severe gastrointestinal symptoms is important.
  • Pioglitazone may cause fluid retention and Edema. Individuals should be monitored for signs of fluid retention, such as swelling, especially in those with a history of heart failure.

Benefits Of Glemin PM 2mg/500mg/15mg Tablet

  • Triple combination for type 2 diabetes .
  • Glimepiride stimulates insulin release.
  • Metformin improves insulin sensitivity .
  • Pioglitazone enhances insulin action

Side Effects Of Glemin PM 2mg/500mg/15mg Tablet

  • Hypoglycemia (low blood glucose level)
  • Dizziness
  • Headache
  • Nausea
  • Weight gain
  • Gastrointestinal disturbance

What If I Missed A Dose Of Glemin PM 2mg/500mg/15mg Tablet

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

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Safety Advice For Glemin PM 2mg/500mg/15mg Tablet

check for risk indication explain below.

  • High risk
  • Moderate risk
  • Safe

Alcohol

It is deemed unsafe to mix alcohol with Glemin PM 2mg/500mg/15mg Tablet due to the possibility of harmful side effects.

Pregnancy

Using Glemin PM 2mg/500mg/15mg Tablet during pregnancy could be risky. Discuss the benefits and potential dangers with your doctor before taking it.

Breast feeding

The data suggests potential harm to the infant, thus Glemin PM 2mg/500mg/15mg Tablet is regarded as unsafe to use while breastfeeding.

Kidney

Use this medicine with caution if you have kidney disease. Dose adjustments and routine kidney function monitoring may be required after consulting your doctor.

Liver

For patients with liver disease, be cautious when taking this medicine. It may need a dosage adjustment and is not recommended for those with severe liver disease.

Alcohol

It is deemed unsafe to mix alcohol with Glemin PM 2mg/500mg/15mg Tablet due to the possibility of harmful side effects.

Pregnancy

Using Glemin PM 2mg/500mg/15mg Tablet during pregnancy could be risky. Discuss the benefits and potential dangers with your doctor before taking it.

Breast feeding

The data suggests potential harm to the infant, thus Glemin PM 2mg/500mg/15mg Tablet is regarded as unsafe to use while breastfeeding.

Kidney

Use this medicine with caution if you have kidney disease. Dose adjustments and routine kidney function monitoring may be required after consulting your doctor.

Liver

For patients with liver disease, be cautious when taking this medicine. It may need a dosage adjustment and is not recommended for those with severe liver disease.

Disease Explanation

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Type 2 diabetes mellitus is a chronic condition that affects how the body regulates and uses sugar (glucose) as a fuel. It occurs when the body becomes resistant to insulin, a hormone that helps glucose enter the cells, or when the pancreas cannot produce enough insulin. As a result, the blood sugar levels become too high and can cause damage to various organs and tissues.