Introduction to Meditinib 400mg Tablet

Meditinib 400mg Tablet is classified within the drug category called tyrosine kinase inhibitors and is primarily prescribed for the management of specific cancers. It's necessary to stick to the advised dosage and duration for maximum effectiveness.

This drug functions by targeting certain proteins called tyrosine kinases, which aid in the proliferation of cancer cells. By disrupting these proteins, Imatinib assists in regulating the proliferation and segregation of cancer cells, playing a valuable role in the management of multiple cancer types.

Patients have the option to consume it with meals or on an empty stomach,, but it's beneficial to take it at a regular time each day for enhanced results.

The treatment may produce a variety of negative reactions, such as fluid retention, extreme tiredness, skin hives, high temperature, alopecia, sleep disturbances, aches in the joints, muscle pains, increase in body weight, nocturnal sweating, itchiness, adverse effects on the digestive system, blood cell irregularities, damage to the liver, and kidney toxicity. Although some of these adverse reactions are standard, any serious or lingering conditions should be reported to the healthcare professional immediately.

The treatment might result in a condition known as tumor lysis syndrome, particularly in patients with a substantial quantity of tumor cells. Regular checks and preventive actions are vital to manage this possible risk. In parallel, if anyone endures severe or continuous muscle or skeletal discomfort or contractions, they should seek out medical help immediately.

Should a dosage be overlooked, it should be taken as soon as remembered. If the subsequent scheduled dosage is near, the omitted dosage shouldn't be doubled. It's wise to reach out to the prescribing doctor for tips on how to effectively handle missed doses.

How Meditinib 400mg Tablet Works?

In a more substantial dose, Meditinib 400mg Tablet retains its designation as a tyrosine kinase inhibitor, proficiently managing aberrant protein performance in cancer cells. This enhanced dosage is typically advised at evolved phases of certain cancers, ensuring sustained impediment of tumor advancement and escalation for better clinical results.

How To Use Meditinib 400mg Tablet

  • Adhere to your physicians' instructions for this medication, consuming it in the instructed dosage and period.
  • You can consume this medication with or without meals, but sustaining a uniform time every day is encouraged for improved outcomes.
  • Ingest the medication wholly; refrain from chewing, pulverizing, or fracturing it.

Special Precautions About Meditinib 400mg Tablet

  • Imatinib treatment may lead to tumour lysis syndrome, especially in individuals with high tumour burden. Monitoring and preventative measures should be implemented to manage this risk.
  • Imatinib may cause musculoskeletal pain or cramps. Individuals experiencing severe or persistent pain should seek medical attention.

Benefits Of Meditinib 400mg Tablet

  • Manages gastrointestinal stromal tumours.
  • Inhibits cancer cell growth.

Side Effects Of Meditinib 400mg Tablet

  • Edema (swelling)
  • Fatigue
  • Rash
  • Fever
  • Hair loss
  • Insomnia (difficulty in sleeping)
  • Joint pain
  • Muscle pain
  • Weight gain
  • Night sweats
  • Itching
  • Gastrointestinal toxicity
  • Blood cell abnormalities
  • Liver toxicity, Renal toxicity

What If I Missed A Dose Of Meditinib 400mg Tablet

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

FAQS

Meditinib 400mg Tablet

Q. Can I expect that if I take Meditinib regularly and as advised by the doctor for CML, I will be cured?

Meditinib has proved effective in many cases of CML. It is also noticed that the chances of survival increase after taking this medicine. The doctor who is treating CML can tell you better. The doctor will analyze your current state, blood test results, response to treatment, any other medical illness which you may be having, etc. and tell you.

Meditinib 400mg Tablet

Q. The doctor has advised me not to take any medicine on my own while taking Meditinib. Should I consult my doctor even if I need to take paracetamol for my fever?

Yes, there are a number of medicines which interfere with Meditinib, including paracetamol. Therefore you should not self medicate while taking Meditinib. Other medicines which interfere with Meditinib include cyclosporin, dexamethasone (a steroid), warfarin, antiviral medicines which treat AIDS and some medicines which treat bacterial infections, high cholesterol, high blood pressure, heart problems, and mental disorders and depression. Consult your doctor before taking any medicine, and inform him that you are on Meditinib therapy.

Meditinib 400mg Tablet

Q. What precautions need to be followed while taking Meditinib?

While taking Meditinib, make sure you follow all the instructions given by your doctor, carefully and keep all appointments. You will need regular follow-up to ensure that the treatment is working. Regular blood tests, weight checks, and urine tests may be required to find out any side effects before it becomes serious. Make sure you use a method of contraception to prevent pregnancy during treatment with Meditinib. Tell your doctor immediately if you become pregnant while you are taking this medicine. If you are about to start taking any new medicine, remind your doctor that you are taking Meditinib.

Meditinib 400mg Tablet

Q. Ever since I started using Meditinib, I have noticed that I develop rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?

This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness or severe sunburn. When you are outdoors, wear protective clothing and use a sunscreen with an SPF of 15 or higher. If you feel a burning sensation on your skin, tell your doctor.

Meditinib 400mg Tablet

Q. Is it safe to drive while taking Meditinib?

Meditinib may cause dizziness, lightheadedness or drowsiness in some people. Make sure you know how you react to it before you drive a car or operate machinery.

Meditinib 400mg Tablet

Q. Can Meditinib be taken with food?

Yes, the best way to take it is with a glass of water and food. This prevents irritation in the food pipe and stomach. If you cannot swallow it, put the tablets in a glass of water or apple juice (approximately 50 ml for a 100 mg tablet and 200 ml for a 400 mg tablet). Stir it with a spoon to make it uniform and drink it immediately.

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Safety Advice For Meditinib 400mg Tablet

check for risk indication explain below.

  • High risk
  • Moderate risk
  • Safe

Alcohol

Consult your healthcare provider for advice on the safety of alcohol consumption while on Meditinib 400mg Tablet.

Pregnancy

It's unsafe to use Meditinib 400mg Tablet during pregnancy because of potential risks to the unborn baby. Please seek advice from your doctor.

Breast feeding

Caution is advised when breastfeeding while using Meditinib 400mg Tablet, as it could potentially harm the baby. Avoid nursing during therapy and for 15 days after discontinuation.

Kidney

For people with kidney disease, Meditinib 400mg Tablet should be used with caution. Your doctor may advise on possible dosage alterations and supervision.

Liver

People with severe liver conditions should be careful with Meditinib 400mg Tablet. Adjustments on dosage might be needed. Consult your physician for personalized recommendations.

Alcohol

Consult your healthcare provider for advice on the safety of alcohol consumption while on Meditinib 400mg Tablet.

Pregnancy

It's unsafe to use Meditinib 400mg Tablet during pregnancy because of potential risks to the unborn baby. Please seek advice from your doctor.

Breast feeding

Caution is advised when breastfeeding while using Meditinib 400mg Tablet, as it could potentially harm the baby. Avoid nursing during therapy and for 15 days after discontinuation.

Kidney

For people with kidney disease, Meditinib 400mg Tablet should be used with caution. Your doctor may advise on possible dosage alterations and supervision.

Liver

People with severe liver conditions should be careful with Meditinib 400mg Tablet. Adjustments on dosage might be needed. Consult your physician for personalized recommendations.

Disease Explanation

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Chronic Myeloid Leukemia (CML): A type of blood cancer that originates in the bone marrow, specifically affecting the white blood cells. CML is characterized by the overproduction of abnormal white blood cells called granulocytes. It often progresses slowly and can be managed with targeted therapies. Acute Lymphocytic Leukemia (ALL): Another type of blood cancer that primarily affects the white blood cells, specifically lymphocytes. ALL is characterized by the rapid and uncontrolled proliferation of immature lymphocytes. It is an aggressive form of leukemia that requires prompt treatment, typically with chemotherapy. Gastrointestinal Stromal Tumor (GIST): A rare type of tumor that originates in the gastrointestinal tract, most commonly in the stomach or small intestine. GISTs are usually non-cancerous (benign), but some can be cancerous (malignant). They are often treated with surgery and, in some cases, targeted therapy to inhibit specific molecular pathways involved in their growth.

Update on: Saturday, 17 Feburary, 2024

Written By:

Written By:

Nitish Chauhan