Nexaparin 40mg Injection
Introduction to Nexaparin 40mg Injection
Nexaparin 40mg Injection falls under the category of low molecular weight heparin (LMWH) and functions mainly as an anticoagulant to hinder the formation of blood clots. Enoxaparin acts by latching onto antithrombin, which in turn deactivates clotting factor Xa involved in coagulation. This mitigates the likeliness of blood clot proliferation.
Given that it belongs to the group of drugs termed as low molecular weight heparins (LMWHs), Enoxaparin is frequently recommended to stall blood clots. It has wide applicability, including the treatment of conditions like deep vein thrombosis (DVT), pulmonary embolism (PE), or in surgical circumstances to prohibit formation of clots.
It's critical that a medical expert perform the administration. Self-administration is not advocated. Strict adherence to the advice dispensed by the medical practitioner or the nurse is necessary.
Side effects may include incidents of bleeding, headaches, a decrease in blood platelet count, enhancement in liver enzyme levels, anemia, fever, discomfort at the injection site, respiratory issues, swells, and diarrhea.
Special attention is warranted when prescribing this medication to patients with an elevated susceptibility to bleeding – those with uncontrolled high blood pressure, recent gastrointestinal hemorrhage, or a past incidence of stroke. There's also a danger of heparin induced thrombocytopenia (HIT), an abrupt plunge in platelet count, which necessitates instant cessation of the medication.
If a dosage is overlooked, it should be consumed as soon as remembered. But if the next planned dosage is imminent, it's better to ignore the missed one & proceed with the usual dosage routine. Avoid increasing dosages unnecessarily and seek medical advisory on how to handle missed dosages optimally.
How Nexaparin 40mg Injection Works?
Nexaparin 40mg Injection, by coupling with antithrombin, generates a compound that durably neutralizes clotting factor Xa, an essential component in the blood coagulation cascade. This process curbs excessive clot creation. Importantly, enoxaparin demonstrates a stronger attraction towards factor Xa compared to factor IIa (thrombin), setting it apart from undifferentiated heparin and enhancing its anticoagulant outcomes by mainly obstructing factor Xa-induced blood coagulation.
How To Use Nexaparin 40mg Injection
- This medication will be given by your physician or nurse; please refrain from self administration.
- Refrain from consuming it independently; wait for instruction from your physician or nurse.
- Rely on your health service provider to deliver the drug; do not try for self administration.
Special Precautions About Nexaparin 40mg Injection
- Enoxaparin, like other heparinbased anticoagulants, can cause heparin induced thrombocytopenia (HIT), a potentially serious condition characterized by a rapid drop in platelet count. If HIT is suspected, enoxaparin should be discontinued immediately.
- Enoxaparin should be used cautiously in patients at an increased risk of hemorrhage, such as those with severe hypertension, recent gastrointestinal bleeding, or a history of stroke.
- Enoxaparin use poses a risk of epidural or spinal hematoma, particularly in individuals undergoing spinal procedures or receiving epidural anesthesia. The use of enoxaparin should be avoided or used with caution in these settings.
Benefits Of Nexaparin 40mg Injection
- Prevents blood clots after surgery.
- It ensures smoother blood flow.
- Safely maintains circulatory health.
Side Effects Of Nexaparin 40mg Injection
- Bleeding
- Headache
- Low blood platelets
- Increased liver enzymes
- Anemia (low number of red blood cells)
- Fever
- Injection site pain
- Breathing problems
- Edema (swelling)
- Diarrhea
What If I Missed A Dose Of Nexaparin 40mg Injection
FAQS
Nexaparin 40mg Injection
Q. Can Nexaparin be used in heart attack?
Yes, Nexaparin is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.
Nexaparin 40mg Injection
Q. How to store Nexaparin injections?
Store Nexaparin injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Discard the injection if you notice any particulate matter or abnormal color in the solution or any damage in the syringe. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.
Nexaparin 40mg Injection
Q. What are the conditions where I should be cautious before taking Nexaparin?
You must give a proper history to your doctor before you start taking Nexaparin. Inform your doctor if you have a heart valve fitted or have gastric ulcer, high blood pressure, diabetes, or kidney problems. You should also let your doctor know if you ever had a reaction to heparin or had a recent stroke, brain or spinal surgery. The chances of side effects and complications increase in presence of these conditions. Consult with your doctor and follow the instructions strictly.
Nexaparin 40mg Injection
Q. Is it ok to inject the air bubble in Nexaparin?
Yes, you should push the air bubbles into the site of injection. Removing the air bubbles leads to loss of the medicine thereby altering the prescribed dose.
Nexaparin 40mg Injection
Q. How do you administer Nexaparin?
Nexaparin is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the healthcare provider strictly. Contact your doctor in case of any doubt or any reactions associated with the medicine.
Nexaparin 40mg Injection
Q. When will I feel better after taking Nexaparin?
Nexaparin reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Nexaparin. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
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Safety Advice For Nexaparin 40mg Injection
check for risk indication explain below.
- High risk
- Moderate risk
- Safe
Alcohol
Seek advice from your healthcare professional regarding the combination of alcohol and medication.
Pregnancy
Based on animal studies, medicine is typically deemed safe during pregnancy, but seek advice from your doctor for individualized guidance.
Breast feeding
The medicine is likely safe during breastfeeding since minimal quantities pass into the breast milk.
Kidney
Patients with kidney disease are advised to be cautious; adjustments may be needed. Please seek advice from your doctor.
Liver
There is scarce information available on the use of this medicine in liver disease; please consult your doctor for advice.
Alcohol
Seek advice from your healthcare professional regarding the combination of alcohol and medication.
Pregnancy
Based on animal studies, medicine is typically deemed safe during pregnancy, but seek advice from your doctor for individualized guidance.
Breast feeding
The medicine is likely safe during breastfeeding since minimal quantities pass into the breast milk.
Kidney
Patients with kidney disease are advised to be cautious; adjustments may be needed. Please seek advice from your doctor.
Liver
There is scarce information available on the use of this medicine in liver disease; please consult your doctor for advice.
Disease Explanation
Blood clots are gel-like clumps of blood that form when the blood coagulates or thickens. They can help stop bleeding from an injury, but they can also cause problems if they block the blood flow in the veins or arteries.
Update on: Tuesday, 23 January, 2024
Written By:
Salman Khan
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