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Introduction to Spegra Tablet 90s
Spegra 50/200/25 mg Tablet is a combination antiretroviral medication used in the treatment of Human Immunodeficiency Virus type 1 (HIV-1) infection. It contains three active ingredients: Dolutegravir (50 mg), Emtricitabine (200 mg), and Tenofovir Alafenamide (25 mg). This combination works synergistically to suppress the replication of HIV-1, thereby enhancing the immune system's function and reducing the risk of developing Acquired Immunodeficiency Syndrome (AIDS).
Safety Advice for Spegra Tablet 90s
- High risk
- Moderate risk
- Safe
Use with caution; consult your doctor.
Generally considered safe; limited human studies, consult your doctor.
Consult your doctor; information not available.
Consult your doctor; effect on driving ability unknown.
Unsafe; avoid use in kidney disease, consult your doctor.
Unsafe; avoid use in liver disease, consult your doctor.
How Spegra Tablet 90s works
Each component of Spegra Tablet plays a crucial role in inhibiting HIV replication: Dolutegravir: An integrase strand transfer inhibitor (INSTI) that blocks the HIV integrase enzyme, preventing the integration of viral DNA into the host cell genome. Emtricitabine: A nucleoside reverse transcriptase inhibitor (NRTI) that inhibits the reverse transcriptase enzyme, blocking the conversion of viral RNA into DNA. Tenofovir Alafenamide: Another NRTI that, once activated in the body, inhibits reverse transcriptase, thereby preventing viral replication. By targeting different stages of the HIV life cycle, Spegra Tablet effectively reduces the viral load in the body.
How To Use Spegra Tablet 90s
- Dosage: Take one Spegra Tablet orally once daily, with or without food, as prescribed by your healthcare provider.
- Administration: Swallow the tablet whole with water; do not crush, chew, or break it.
- Consistency: Take the medication at the same time each day to maintain consistent blood levels.
- Missed Dose: If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose. Do not double the dose to catch up.
Special Precautions About Spegra Tablet 90s
- Allergies: Inform your doctor if you have known allergies to any components of Spegra Tablet.
- Medical History: Disclose any history of liver or kidney disease, osteoporosis, or other significant health conditions.
- Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
- Drug Interactions: Provide a complete list of all medications, supplements, and herbal products you are taking to avoid potential interactions.
Benefits Of Spegra Tablet 90s
- Viral Suppression: Spegra Tablet reduces HIV-1 viral load, helping to prevent progression to AIDS.
- Immune System Support: Enhances immune function by increasing CD4+ T-cell counts.
- Convenience: Combines three antiretroviral agents into a single daily tablet, simplifying treatment regimens.
Side Effects Of Spegra Tablet 90s
- Common side effects may include: Headache, Nausea, Diarrhea, Fatigue, Insomnia.
- Serious side effects are rare but may include liver toxicity, kidney impairment, or severe allergic reactions.
- Contact your healthcare provider if you experience symptoms such as yellowing of the skin or eyes, dark urine, persistent nausea or vomiting, or rash.
Similar Medicine Of Spegra Tablet 90s
What If I Missed A Dose Of Spegra Tablet 90s
- Consistency is key in HIV treatment.
- If you miss a dose of Spegra Tablet take as Soon as Possible.
- If you remember shortly after the missed dose, take it immediately.
- If it's almost time for your next scheduled dose, skip the missed dose.
- Do not take two doses at once to make up for a missed dose.
Health And Lifestyle
Diet: Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support overall health. Exercise: Engage in regular physical activity to boost immune function and maintain bone health. Hydration: Drink plenty of fluids to stay hydrated. Avoid Alcohol and Recreational Drugs: These can weaken the immune system and interact negatively with your medication. Safe Practices: Use protection during sexual activity and avoid sharing needles to prevent the spread of HIV.
Drug Interaction
- Dofetilide: Co-administration is contraindicated due to the risk of serious heart rhythm problems.
- Antacids: Products containing aluminum, magnesium, or calcium can reduce the absorption of Dolutegravir. Take antacids at least two hours before or six hours after Spegra Tablet.
- Rifampin: May decrease the effectiveness of Spegra Tablet. Dose adjustments may be necessary.
- Anticonvulsants: Medications like carbamazepine and phenytoin can lower the levels of Spegra components in the blood.
- Herbal Supplements: St. John's Wort may reduce the effectiveness of Spegra Tablet.
Drug Food Interaction
- High-Fat Meals: While Spegra Tablet can be taken with or without food, high-fat meals may delay its absorption.
- Alcohol: Avoid alcohol consumption, as it may increase the risk of liver toxicity and reduce the effectiveness of the medication.
- Grapefruit Juice: While not a well-documented interaction, it's best to consult your doctor about consuming grapefruit juice while on antiretroviral therapy.
Disease Explanation
HIV/AIDS (Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome) HIV is a virus that attacks the immune system, specifically CD4+ T-cells, weakening the body's ability to fight infections and diseases. If left untreated, HIV can progress to AIDS, the most severe stage, where the immune system is significantly compromised. Spegra Tablet is part of Antiretroviral Therapy (ART), which helps suppress viral replication, preventing disease progression and improving quality of life.
Tips of Spegra Tablet 90s
Adhere to Treatment: Take your Spegra Tablet consistently to maintain viral suppression.,Regular Medical Checkups: Monitor your viral load and CD4+ counts with routine blood tests.,Healthy Lifestyle: Eat a balanced diet, exercise regularly, and manage stress to support immune function.,Prevent Transmission: Use protective measures like condoms and avoid sharing needles.,Stay Educated: Keep yourself informed about advancements in HIV treatment and care.
FactBox of Spegra Tablet 90s
- Drug Name: Spegra 50/200/25 mg Tablet
- Composition: Dolutegravir 50 mg, Emtricitabine 200 mg, Tenofovir Alafenamide 25 mg
- Uses: Treatment of HIV-1 infection
- Dosage: One tablet daily
- Administration: Oral, with or without food
- Common Side Effects: Nausea, headache, diarrhea, fatigue
- Storage: Store below 30°C, away from moisture and heat
- Drug Class: Antiretroviral Therapy (ART)
Storage of Spegra Tablet 90s
- Store Spegra Tablet in a cool, dry place below 30°C.
- Keep the medication in its original packaging to protect it from moisture.
- Keep out of reach of children and pets.
- Do not use the medication past its expiration date.
Dosage of Spegra Tablet 90s
Standard Dose: One Spegra Tablet once daily.,Overdose Management: In case of an overdose, seek immediate medical attention. Symptoms may include severe nausea, dizziness, or trouble breathing.
Synopsis of Spegra Tablet 90s
Spegra 50/200/25 mg Tablet is a combination of Dolutegravir, Emtricitabine, and Tenofovir Alafenamide, used to treat HIV-1 infection. It works by preventing the virus from multiplying, reducing viral load, and strengthening the immune system. Taken once daily, it helps prevent the progression of HIV to AIDS when used consistently.
FAQ's on Spegra Tablet 90s
What is Spegra Tablet used for?
Spegra Tablet is used to treat HIV-1 infection by reducing the virus''s ability to multiply, helping improve immune function.
Can Spegra Tablet cure HIV?
No, Spegra does not cure HIV, but it helps manage the infection effectively and prevents disease progression.
How long does Spegra take to work?
Spegra starts working immediately, but it may take weeks or months to significantly reduce viral load. Regular blood tests are necessary to monitor progress.
Can I stop taking Spegra once my viral load is undetectable?
No, stopping treatment can cause the virus to return and develop resistance. Always follow your doctor''s advice.
What should I do if I experience side effects?
If side effects are mild, they may go away on their own. For severe reactions, consult your doctor immediately.
Can pregnant women take Spegra Tablet?
Pregnant women should consult their doctor before taking Spegra, as the benefits and risks must be evaluated.
Is Spegra safe for kidney patients?
Spegra may affect kidney function. If you have kidney disease, discuss alternative treatments with your doctor.
Can I drink alcohol while taking Spegra?
It''s best to avoid alcohol, as it may increase the risk of liver toxicity and worsen side effects.
Can I take Spegra with other medications?
Spegra interacts with certain drugs, including antacids, anticonvulsants, and rifampin. Inform your doctor about all medications you take.
Is Spegra suitable for children?
Spegra is generally prescribed for adults. For pediatric use, consult a healthcare professional.
How does Spegra compare to other HIV medications?
Spegra is a fixed-dose combination offering convenience and effectiveness, reducing the need for multiple pills.
Can I take Spegra if I have hepatitis B?
Patients with hepatitis B should consult their doctor, as stopping treatment may cause severe liver complications.
Will Spegra affect my fertility?
There is no evidence suggesting that Spegra impacts fertility in men or women.
Can I travel while taking Spegra?
Yes, but carry enough medication for your trip and store it properly.
Does Spegra cause weight gain?
Some patients report minor weight changes, but this varies from person to person.
Can I donate blood while taking Spegra?
No, individuals with HIV should not donate blood, even if their viral load is undetectable.
How does Spegra improve my quality of life?
By suppressing HIV replication, Spegra helps prevent complications, prolongs life expectancy, and allows patients to lead healthier lives.
Can I take Spegra with herbal supplements?
Some herbal supplements, such as St. John''s Wort, can reduce Spegra''s effectiveness. Consult your doctor before using supplements.
What happens if I miss multiple doses?
Missing multiple doses may lead to drug resistance. Restart treatment as soon as possible and inform your doctor.
Does Spegra cause mood changes?
Some patients report mood swings or depression. If you experience severe changes, consult a healthcare provider.
Written By
Nish Kumar
B.Pharma + MBA
Content Updated on
Thursday, 27 Feburary, 2025Prescription Required
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