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Introduction to Versavo 400 Solution for Infusion 16ml
Versavo 400 Solution for Infusion is an anti-cancer medication used in the treatment of various cancers, including colorectal cancer, lung cancer, kidney cancer, and brain tumors. It contains Bevacizumab (400mg/16ml), a monoclonal antibody that works by blocking the formation of new blood vessels (angiogenesis) that supply tumors with nutrients, thereby slowing or stopping their growth.
Safety Advice for Versavo 400 Solution for Infusion 16ml
- High risk
- Moderate risk
- Safe
Avoid alcohol as it may increase dizziness and side effects.
Use with caution; regular monitoring needed.
Use with caution; regular monitoring needed.
Not safe during pregnancy; use effective contraception.
Avoid, as Bevacizumab may harm the baby.
Avoid driving if you experience dizziness, vision problems, or fatigue.
How Versavo 400 Solution for Infusion 16ml works
Bevacizumab (400mg/16ml): Inhibits vascular endothelial growth factor (VEGF), preventing the formation of new blood vessels that tumors need to grow. This starves the tumor of nutrients and oxygen, slowing its progression.
How To Use Versavo 400 Solution for Infusion 16ml
- Dosage: As prescribed by the oncologist.
- Administration: Given as an intravenous (IV) infusion over 30-90 minutes.
- Frequency: Usually every 2-3 weeks, depending on cancer type and patient response.
- Duration: Treatment may continue until the disease progresses or side effects become severe.
Special Precautions About Versavo 400 Solution for Infusion 16ml
- High Blood Pressure: Bevacizumab can cause hypertension; regular monitoring is required.
- Surgery & Wound Healing: Avoid use before or after surgery, as it can delay wound healing.
- Bleeding Risk: Can increase the risk of bleeding and blood clots.
- Heart Patients: Use with caution if you have heart disease or a history of stroke.
Benefits Of Versavo 400 Solution for Infusion 16ml
- Slows Tumor Growth: Inhibits blood supply to tumors, starving them of nutrients.
- Improves Survival Rate: Extends progression-free survival in cancer patients.
- Works with Other Therapies: Often used with chemotherapy for enhanced effectiveness.
- Treats Multiple Cancers: Effective for colorectal, lung, kidney, ovarian, and brain tumors.
Side Effects Of Versavo 400 Solution for Infusion 16ml
- Common Side Effects: High blood pressure, nosebleeds, fatigue, nausea, diarrhea.
- Serious Side Effects: Internal bleeding, blood clots, kidney damage, heart attack, stroke.
- Rare Side Effects: Perforation of the stomach or intestines (life-threatening emergency).
Similar Medicine Of Versavo 400 Solution for Infusion 16ml
What If I Missed A Dose Of Versavo 400 Solution for Infusion 16ml
- If you miss an appointment, reschedule as soon as possible.
- Do not take extra doses to compensate for a missed infusion.
Health And Lifestyle
Monitor Blood Pressure: High blood pressure is a common side effect; check it regularly. Eat a Balanced Diet: Include nutrient-rich foods to support overall health. Avoid Smoking & Alcohol: These can increase side effects and interfere with treatment. Stay Hydrated: Drink plenty of fluids to help kidney function. Regular Blood Tests: Monitor for kidney function, blood clot risk, and white blood cell count.
Drug Interaction
- Chemotherapy Drugs (e.g., Cisplatin, Paclitaxel): Increases risk of kidney damage.
- Blood Thinners (e.g., Warfarin, Heparin): Raises bleeding risk.
- NSAIDs (e.g., Ibuprofen, Aspirin): Can increase risk of gastrointestinal bleeding.
- Anti-Hypertensive Medications: May need dose adjustments due to increased blood pressure.
Disease Explanation
Colorectal Cancer Cancer of the colon or rectum, commonly treated with a combination of chemotherapy and targeted therapies like Bevacizumab to slow tumor growth. Lung Cancer Non-small cell lung cancer (NSCLC) is often treated with Bevacizumab plus chemotherapy to improve survival. Kidney Cancer (Renal Cell Carcinoma) Bevacizumab is used with interferon-alpha therapy to inhibit tumor blood supply. Brain Tumors (Glioblastoma Multiforme) Used in recurrent glioblastoma to reduce brain swelling and slow tumor progression.
Tips of Versavo 400 Solution for Infusion 16ml
Administer by a Healthcare Professional: Do not self-administer.,Keep Out of Reach of Children: For hospital use only.,Do Not Shake or Dilute at Home: Must be prepared by a professional.
FactBox of Versavo 400 Solution for Infusion 16ml
- Product Name: Versavo 400 Solution for Infusion
- Manufacturer: Dr. Reddy’s Laboratories Ltd
- Salt Composition: Bevacizumab (400mg/16ml)
- Uses: Treats colorectal cancer, lung cancer, kidney cancer, ovarian cancer, and brain tumors
- Dosage Form: Intravenous infusion
- Route of Administration: IV (Hospital Use Only)
- Storage: Store between 2-8°C (refrigerated), do not freeze
Storage of Versavo 400 Solution for Infusion 16ml
Store at 2-8°C: Keep refrigerated, but do not freeze.
Dosage of Versavo 400 Solution for Infusion 16ml
Recommended Dosage: 5-15mg/kg every 2-3 weeks, based on cancer type.
FAQ's on Versavo 400 Solution for Infusion 16ml
Can Versavo 400 be used alone, or does it require chemotherapy?
It is usually given with chemotherapy for better results, but in some cases, it may be used alone.
How long can a patient stay on Versavo 400?
Treatment continues until the disease worsens or side effects become intolerable.
Can Versavo cure cancer?
No, it slows tumor growth and extends survival, but it is not a cure.
Does Versavo 400 cause hair loss?
No, hair loss is uncommon with Bevacizumab, but it may occur due to chemotherapy.
What should I avoid while receiving Versavo treatment?
Avoid NSAIDs, alcohol, and elective surgeries during treatment.
Can Versavo 400 affect fertility?
Yes, it may affect ovarian function and fertility. Discuss fertility options with your doctor.
How does Versavo compare to Avastin?
Versavo is a biosimilar of Avastin (Bevacizumab), offering the same effectiveness at a lower cost.
Can Versavo 400 cause high blood pressure?
Yes, regular blood pressure monitoring is necessary.
Is Versavo 400 safe for elderly patients?
Yes, but elderly patients may require closer monitoring for side effects.
What happens if I miss an infusion?
Reschedule as soon as possible; missing doses may reduce effectiveness.
Can Versavo 400 be used for breast cancer?
Bevacizumab (Versavo) was previously approved for breast cancer, but its approval was withdrawn for this use in some countries due to limited benefits. However, some doctors may still prescribe it off-label.
How does Versavo 400 affect wound healing?
It can delay wound healing, so it should not be used before or soon after surgery. Doctors typically stop it at least 28 days before surgery and restart once healing is complete.
Can I receive Versavo 400 if I have a history of blood clots?
Use with caution if you have a history of deep vein thrombosis (DVT), stroke, or pulmonary embolism, as Bevacizumab increases clotting risks.
Does Versavo 400 cause weight loss?
Some patients may experience weight loss due to appetite changes, nausea, or cancer-related effects, but the drug itself does not directly cause weight loss.
Can Versavo 400 cause kidney damage?
Yes, it can cause proteinuria (protein in urine), which may indicate kidney damage. Regular urine tests and kidney function monitoring are advised.
Is there a generic version of Versavo?
Versavo itself is a biosimilar of Avastin (Bevacizumab), meaning it is a more affordable version with the same effectiveness.
Can Versavo 400 be combined with immunotherapy?
Yes, Bevacizumab is often combined with immunotherapy drugs like Atezolizumab (Tecentriq) for lung and liver cancer.
What should I do if I develop high blood pressure while on Versavo?
Your doctor may prescribe blood pressure medication to manage this side effect. Regular monitoring is essential.
Can Versavo 400 cause vision problems?
In rare cases, it may cause blurry vision or eye pain due to increased blood pressure or blood clot risk. Seek medical attention if this occurs.
Does Versavo 400 interact with radiation therapy?
It is usually not given with radiation therapy as it may increase the risk of tissue damage and bleeding.
Written By
Pranav ayush
MBA in Pharmaceutical
Content Updated on
Saturday, 22 Feburary, 2025Prescription Required
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