Similar Medicine Of Amicobal 10mg/1500mcg Tablet
Discover the Benefits of ABHA Card registration
Simplify your healthcare journey with Indian Government's ABHA card. Get your card today!
Create ABHAIntroduction to Amicobal 10mg/1500mcg Tablet
It is an antidepressant that has calming and sedative effects. It works by stopping the breakdown of two chemicals in the brain, noradrenaline and serotonin, which help in improving mood. The drug also blocks pain signals from reaching the brain, which helps in relieving nerve pain.
How Amicobal 10mg/1500mcg Tablet works
It is a combination of two medicines: Amitriptyline and methylcobalamin. Amitriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B that helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
How To Use Amicobal 10mg/1500mcg Tablet
- Take this medicine in the dose and duration as advised by your doctor.
- Swallow it as a whole. Do not chew, crush or break it.
- It may be taken with or without food, but it is better to take it at a fixed time.
Special Precautions About Amicobal 10mg/1500mcg Tablet
- Tell your doctor about any other health issues or medications that you are taking, as they may affect this medicine.
- Inform your doctor if you are either pregnant or breastfeeding.
Benefits Of Amicobal 10mg/1500mcg Tablet
- Helps to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury.
- It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness.
- Provide relief from nerve pain.
- Nutritional supplements improve nerve conduction.
Side Effects Of Amicobal 10mg/1500mcg Tablet
- Constipation
- Difficulty in urination
- Weight gain
- Dryness in mouth
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Drowsiness
- Blurred vision
- Increased heart rate
What If I Missed A Dose Of Amicobal 10mg/1500mcg Tablet
- Use the medicine as you remember to take.
- If the next dose is near then Skip the missed Dose.
- Do not double up for the missed Dose.
- If you miss doses frequently then consult your Doctor.
Health And Lifestyle
Drug Interaction
- Monoamine oxidase inhibitors : moclobemide, phenelzine
- selegiline
Drug Food Interaction
- Alcohol
Disease Explanation

Neuropathic pain is caused by malfunctioning or damaged nerve fibers in the nervous system, affecting peripheral nerves, spinal cord, and brain. Damaged nerve fibers send incorrect signals to pain centers, causing central sensitization.
Safety Advice for Amicobal 10mg/1500mcg Tablet
- High risk
- Moderate risk
- Safe
It is unsafe to consume alcohol with it.
It may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
It may impair your alertness which may affect your ability to drive.
It is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of drug may not be needed in these patients. Please consult your doctor.
It should be used with caution in patients with liver disease. Dose adjustment of this drug may be needed. Please consult your doctor. Use of drug is not recommended in patients with severe liver disease.
Written By
Rakshita Garg
M.Pharma
Content Updated on
Wednesday, 25 September, 2024