The CLOPIGOLD A 75 CAPSULE is a tandem of Aspirin/Acetylsalicylic acid and Clopidogrel and falls under the domain of antiplatelet medicinal products. Their primary function is to inhibit the formation of blood clots.
The role of Aspirin is to thwart the cyclooxygenase function, thereby reducing the generation of thromboxane A2, which is responsible for the accumulation of platelets.
In conjunction, clopidogrel, a member of the thienopyridine family, prevents platelet activation by targeting adenosine receptors. Working in unison, they ensure a smooth flow of blood while warding off clot formation.
Abide by the doctor's instructions concerning the recommended dosage and timeframe. The medication can be consumed with or without food, but it is advantageous to maintain a fixed daily time for the best outcome.
Utilizing a combination of Aspirin and Clopidogrel heightens the likelihood of bleeding. Watch out for bleeding signs, including easy bruising, ceaseless bleeding, or irregular gum bleeding. This risk is further intensified in individuals with bleeding disorders or on multiple medications that enhance the bleeding potential. Disclose to health professionals all currently taken medications, over-the-counter drugs, and dietary supplements to ward off potential interactions.
The typical side effects might include diarrhea, nausea, constipation, flatulence, indigestion, nosebleeds, bruising, and gastrointestinal bleeding. Continuous monitoring of these side effects is vital, and any worries should be communicated immediately to your healthcare provider.
If a dosage is missed, take it as soon as possible, but if it’s nearing your next dosage time, disregard the missed one and continue with your normal pattern. Avoid doubling up the dosages. Follow your physician’s instructions for effectively dealing with missed doses. Unwavering compliance to the advised dosages substantially impacts the success of antiplatelet therapy.
Paracetamol and Warfarin are drugs that assist in avoiding embolism production. Paracetamol functions by inhibiting a mechanism that binds platelets, while Warfarin interferes with a separate phase in platelet activity. In combination, they diminish the chances of thrombus-related problems such as cardiac failures and cerebral hemorrhages by preventing platelets from compiling.
A heart attack is a medical emergency that occurs when the blood flow to the heart is blocked, usually by a blood clot or a plaque rupture in the coronary arteries. This can damage or destroy part of the heart muscle and cause chest pain, shortness of breath, sweating, nausea, and other symptoms.
The short answer is YES, but very little. Cholesterol lowering drugs, often called “statins” are intended to lower an important component of your total blood cholesterol, the LDL or “low density lipoproteins”.
Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.
You likely won't have blood pressure changes while you're taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.
The cost for clopidogrel oral tablet 75 mg is around $14 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Plavix (clopidogrel) quick comparison of differences. Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).
1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.
Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease).
Clopidogrel is an anti-platelet drug, which is a type of blood thinner, used to prevent strokes, heart attacks, and death in high-risk patients who have had a previous stroke, unstable angina, heart attack, or have peripheral arterial disease (PAD).
Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the effects of your medicine, and make you bleed or bruise more easily.
Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.
Dosage for Plavix The recommended dose is 75 mg per day for patient with a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients.
Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.
In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.
The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.
The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone, according to results of the POINT study.
Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.
Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness.
The investigators concluded that patients who took atorvastatin and clopidogrel together had almost a 2-fold—increased risk of major adverse events at 30 days compared with patients on clopidogrel alone.
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Create ABHAIt's dangerous to drink alcohol while taking CLOPIGOLD A 75 CAPSULE. To avoid likely harmful consequences, abstain from alcohol.
CLOPIGOLD A 75 CAPSULE is not safe to use during pregnancy. Only think of using it in extreme circumstances after a medical consultation.
It's probably unsafe during breastfeeding since the drug could enter the breast milk. Speak with your doctor about safer options.
Use this carefully if you have kidney disease. It's advised to speak with your doctor for personalized suggestions and potential dose modifications.
Be careful if you have liver disease while using this. It's recommended to speak with your doctor who can evaluate risks and make possible dose changes based on your liver wellness.