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Introduction to Coxerin 250mg Capsule
Coxerin 250mg Capsule is an antibiotic medication used for the treatment of multi-drug resistant tuberculosis (MDR-TB) when other first-line drugs fail. It contains Cycloserine (250mg), which works by inhibiting the growth of Mycobacterium tuberculosis, the bacteria responsible for tuberculosis (TB). This medication is part of a combination therapy and should be used under strict medical supervision.
Tuberculosis is a severe bacterial infection that primarily affects the lungs but can spread to other parts of the body, such as the brain, kidneys, and spine. MDR-TB is a form of TB that does not respond to traditional first-line drugs like isoniazid and rifampicin, making treatment more complex and prolonged. Coxerin 250mg Capsule is an essential second-line treatment option that helps combat resistant strains of TB.
It is important to follow the prescribed dosage and complete the full treatment course to prevent the development of further drug resistance. This medicine can cause neurological and psychiatric side effects, so regular monitoring by a doctor is necessary.
Safety Advice for Coxerin 250mg Capsule
- High risk
- Moderate risk
- Safe
Avoid alcohol consumption while taking Coxerin 250mg Capsule, as it increases the risk of severe neurological side effects, including seizures and confusion.
Coxerin 250mg is generally not recommended during pregnancy unless absolutely necessary, as it may affect fetal development. Consult a doctor before use.
The medicine passes into breast milk and may harm a nursing baby. Breastfeeding mothers should consult their doctor before taking this medication.
Coxerin 250mg can cause drowsiness, dizziness, and confusion. Avoid driving or operating heavy machinery until you know how the medicine affects you.
Patients with kidney disease should take Coxerin 250mg with caution, as improper kidney function can lead to drug accumulation and increased toxicity.
Liver patients should also use Coxerin 250mg cautiously. Regular liver function tests (LFTs) may be required to monitor the drug’s effects.
How Coxerin 250mg Capsule works
Coxerin 250mg Capsule contains Cycloserine (250mg), an antibiotic that works by inhibiting the synthesis of bacterial cell walls, preventing the growth and multiplication of Mycobacterium tuberculosis. It specifically blocks the action of enzymes involved in bacterial cell wall formation, leading to bacterial death. Unlike other TB drugs, Cycloserine is effective against drug-resistant strains, making it a valuable option in MDR-TB treatment. However, it is always used in combination with other anti-TB drugs to improve effectiveness and prevent further resistance.
How To Use Coxerin 250mg Capsule
- Take Coxerin 250mg Capsule as prescribed by your doctor, usually on an empty stomach or 1-2 hours before meals.
- Swallow the capsule whole with water. Do not crush, chew, or break it.
- Maintain a consistent dosing schedule to achieve the best results.
- If stomach upset occurs, take it with food but inform your doctor.
Special Precautions About Coxerin 250mg Capsule
- Patients with a history of mental health disorders (depression, anxiety, or psychosis) should use this medicine with caution.
- Regular kidney and liver function tests are required to monitor the medicine’s effects.
- Avoid abruptly stopping Coxerin 250mg Capsule, as it may worsen TB infection.
- Inform your doctor if you have a history of seizures or epilepsy, as Cycloserine may increase the risk of seizures.
- Do not self-medicate or change the dosage without consulting a doctor.
Benefits Of Coxerin 250mg Capsule
- Coxerin Capsule is effective in treating multi-drug resistant tuberculosis (MDR-TB).
- Works against TB bacteria that do not respond to first-line drugs.
- Helps prevent further bacterial resistance when used correctly.
- Supports combination therapy, improving overall TB treatment outcomes.
Side Effects Of Coxerin 250mg Capsule
- Dizziness
- Drowsiness
- Headache
- Nausea and vomiting
- Irritability and anxiety
Similar Medicine Of Coxerin 250mg Capsule
What If I Missed A Dose Of Coxerin 250mg Capsule
- Take the missed dose as soon as you remember.
- If it’s close to the next scheduled dose, skip the missed dose.
- Do not double the dose to make up for a missed one.
- Maintain a consistent dosing schedule for effectiveness.
Health And Lifestyle
Follow a nutritious diet rich in protein, vitamins, and minerals to support recovery. Avoid stress and anxiety, as mental health is important during TB treatment. Get regular exercise, but do not overexert yourself. Take adequate rest and sleep to boost immunity. Avoid smoking and alcohol, as they can interfere with TB medications.
Drug Interaction
- Avoid combining with alcohol, antidepressants, and sedatives, as they may worsen neurological side effects.
- May interact with anticonvulsants and increase the risk of seizures.
- Some antibiotics and antifungal medicines may alter the effectiveness of Coxerin 250mg.
Drug Food Interaction
- Avoid caffeine and energy drinks, as they may worsen nervous system side effects.
- Limit high-fat meals, as they can slow down absorption.
- Vitamin B6 (pyridoxine) supplementation may help reduce neurological side effects.
Disease Explanation
Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis. MDR-TB refers to TB that is resistant to first-line anti-TB drugs, making it more difficult to treat. This condition requires second-line drugs like Cycloserine for effective management.
Tips of Coxerin 250mg Capsule
Take Coxerin 250mg at the same time every day.,Do not skip doses, as this can lead to drug resistance.,Get regular check-ups to monitor treatment progress.,Store the medicine properly to maintain its effectiveness.
FactBox of Coxerin 250mg Capsule
- Generic Name: Cycloserine
- Drug Class: Second-line anti-TB antibiotic
- Primary Use: Multi-drug resistant tuberculosis (MDR-TB) treatment
- Available Strength: 250mg
Storage of Coxerin 250mg Capsule
- Store at room temperature (below 30°C).
- Keep away from moisture and direct sunlight.
- Store in an airtight container to prevent contamination.
- Keep out of reach of children.
Dosage of Coxerin 250mg Capsule
Take this medication as prescribed by your doctor.,Dose adjustments may be required for kidney and liver patients.,Treatment duration varies based on disease severity and response.
Synopsis of Coxerin 250mg Capsule
Coxerin 250mg Capsule (Cycloserine) is a second-line anti-TB drug used for the treatment of multi-drug resistant tuberculosis (MDR-TB). It works by inhibiting bacterial cell wall synthesis, helping control bacterial growth. This medicine is prescription-only and should be taken under strict medical supervision.
It is essential to follow the complete course of treatment to prevent further drug resistance. Side effects such as neurological disturbances and mood changes require close monitoring. Patients should maintain a healthy lifestyle, avoid alcohol, and regularly check in with their doctor for treatment progress.
By adhering to the prescribed regimen and taking necessary precautions, Coxerin 250mg Capsule can significantly aid in MDR-TB treatment and recovery.
FAQ's on Coxerin 250mg Capsule
What is Coxerin 250mg Capsule used for?
Coxerin 250mg Capsule is used to treat multi-drug resistant tuberculosis (MDR-TB) when first-line TB medications fail. It works by stopping the growth of Mycobacterium tuberculosis.
How does Coxerin 250mg work?
Coxerin 250mg contains Cycloserine, which inhibits bacterial cell wall synthesis, preventing the bacteria from growing and multiplying, ultimately helping in treating tuberculosis.
Can Coxerin 250mg be taken on an empty stomach?
Yes, it is best taken on an empty stomach (1 hour before or 2 hours after meals). However, if you experience stomach discomfort, you can take it with food after consulting your doctor.
Can Coxerin 250mg cause depression or anxiety?
Yes, it may cause mood changes, depression, or anxiety, especially in patients with a history of mental health disorders. Inform your doctor if you notice any unusual behavioral changes.
How long should I take Coxerin 250mg?
The duration depends on the severity of MDR-TB and your prescription. TB treatment usually lasts for 6 months to 2 years. Always complete the full course to prevent resistance.
Can Coxerin 250mg be stopped suddenly?
No, stopping suddenly may lead to worsening infection and drug resistance. Always follow instructions of your doctor for dose adjustments or discontinuation.
Can I drive while taking Coxerin 250mg?
Avoid driving as Coxerin 250mg may cause drowsiness, dizziness, or confusion, affecting your ability to operate heavy machinery or vehicles.
Can Coxerin 250mg be taken with other TB medications?
Yes, it is always used in combination with other anti-TB drugs to increase effectiveness and prevent drug resistance.
Are there any food restrictions while taking Coxerin 250mg?
Avoid caffeine, alcohol, and energy drinks, as they may worsen nervous system side effects. Also, take Vitamin B6 (Pyridoxine) to reduce neurological side effects.
Can Coxerin 250mg be used for infections other than TB?
No, Coxerin is specifically used for tuberculosis and is not effective for other bacterial infections.
Can Coxerin 250mg cause seizures?
Yes, in some patients, it may increase the risk of seizures, especially if taken with alcohol, caffeine, or certain other medications. Consult your doctor if you have a history of epilepsy.
Is Coxerin 250mg available without a prescription?
No, it is a prescription-only medicine and should be used under strict medical supervision due to its potential side effects and resistance concerns.
Written By
Priyanka Sonkushre
Content Updated on
Thursday, 24 April, 2025Prescription Required
Coxerin 250mg Capsule
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