Thus, gliclazide causes less hypoglycemia than other sulfonylureas. In CKD sage 1, 2, 3 (eGFR > 30 mL/min) gliclazide can be used. There are no data in patients with severe CKD but according to its metabolism the use (in reduced dose) of gliclazide is also permitted in these subjects[19].

Gliclazide 80 mg can be given in combination with biguanides, alpha glucosidase inhibitors or insulin. In patients not adequately controlled with Gliclazide 80 mg, concomitant insulin therapy can be initiated under close medical supervision.

Metformin is still the safest and most effective type 2 diabetes medication, said Bolen. She is an assistant professor of medicine at Case Western Reserve Universitys Center for Health Care Research and Policy, in Cleveland.

In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis. In patients who show abnormal liver function tests, the immediate discontinuation of gliclazide is recommended.

Yes, Glizid and metformin can be taken at the same time but only if prescribed by the doctor. Your doctor may have prescribed taking the two together to control your uncontrolled sugar levels. However, taking the two together may cause low blood sugar which may also occur if you delay or miss a meal, exercise more than usual or take it with insulin. Follow the instructions given by your doctor strictly to avoid such complications.

No, Glizid is not harmful if your kidney function is normal. Any previous case of kidney problem should be informed to the doctor, so that the use of Glizid can be assessed. This is done in order to analyze whether Glizid can be given or not because it is principally excreted by the kidney. If you have kidney problems you will be started at a lower dose.

No, Glizid is not the same as metformin. Although both these oral medicines are used in the treatment of type 2 diabetes, the way they work to reduce the sugar levels are different. While Glizid acts by increasing the secretion of insulin by the pancreas, metformin acts by improving the functioning and effectiveness of the insulin already available in the body.

Glizid-M Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise.

Take Glizid before meals or exactly as instructed by your doctor. There is evidence stating that Glizid works best at controlling post meal high blood sugar levels when taken 30 minutes before breakfast. So, if you are supposed to take it once daily, take it in the morning before breakfast with a glass of water.

It is important to consider the time-action profile of gliclazide together with information about the patients diet and activity. If given with breakfast it will potentially lower blood glucose levels up to the evening meal. If given with evening meal it will lower blood glucose levels pre bed and during night.

When taken 30 minutes before breakfast, gliclazide produced a peak of IRI 30 minutes after the meal; taken immediately before or after, it took twice to three times as long to produce an IRI peak.

Gliclazide is a medicine used to treat type 2 diabetes. Type 2 diabetes is an illness where the body does not make enough insulin, or the insulin thats made does not work properly. This causes high blood sugar (hyperglycaemia). Gliclazide lowers your blood sugar by increasing the amount of insulin your body produces.