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Introduction to Graftide 500mg Tablet
This medicine belongs to a group of immunosuppressants. This is used in combination with other medicines and prevents the body from graft rejection (rejection of an organ). The body's immune system tends to eliminate the transplanted organ from body so suppressing the immune system helps to prevent the new organ.
Safety Advice for Graftide 500mg Tablet
- High risk
- Moderate risk
- Safe
Limited information available regarding the safety of using this medicine in patients suffering from liver disease.
It should be used cautiously among kidney patients; dose adjustment may required.
Alcohol consumption with this drug does not show any harmful interaction.
It does not seem to impair the driving ability.
It is unsafe to use during pregnancy as it may cause abortion or birth defects.
It is unsafe to use while breastfeeding an infant; it may pass through breast milk to the developing baby.
How Graftide 500mg Tablet works
This medicine contains Mycophenolate mofetil which has immunity-suppressing properties. It reduces the action of the body's defense system and prevents rejection of the transplanted organ.
How To Use Graftide 500mg Tablet
- The dose and frequency of medicine sepends on the type of transplant.
- One should strictly follow the healthcare professional's advise.
- Take the medicine on an empty stomach.
- Swallow the drug as a whole with a full glass water without chewing, crushing, and breaking it.
- Maintain consistency for optimal results.
Special Precautions About Graftide 500mg Tablet
- Avoid infection-causing elements or stay from people suffering communicable disease as suppressed immune system may make you more prone to catch infections.
- It may increase the risk of developing some cancers.
- Be cautious of sun exposure and use sunscreen while going out to reduce the risk of skin cancers.
- Avoid using it if planning to concieve, pregnancy, and breastfeeding.
- Before staring the treatment; discuss openly to your doctor if having unexpected bleeding/bruising or any other signs of infection.
- Expose other medicines you are taking to your heathcare professional.
Benefits Of Graftide 500mg Tablet
- It lowers the immune response and protect body from attacking the transplanted organ.
- Organ rejection occurs when the immune system treats the transplanted organ as an invader and attacks it.
- This medicine is prescribed in combination with other medicines to suppress the immune system and help the body accept the transplanted organ.
Side Effects Of Graftide 500mg Tablet
- Bacterial infection
- Decreased phosphate level in blood
- Fungal infection
- Decreased potassium level in blood
- Viral infection
- Increased potassium level in blood
- Anemia (low number of red blood cells)
- Increased glucose level in blood
- Decreased white blood cell count (lymphocytes)
- Confusion
- High blood pressure
- Depression
- Headache
- Anxiety
- Flatulence
- Insomnia (difficulty in sleeping)
- Fast heart rate
- Tremors
- Dizziness
- Blood in urine
- Vomiting
- Cough
- Breathlessness
- Constipation
- Nausea
- Abdominal pain
- Diarrhea
- Indigestion
Similar Medicine Of Graftide 500mg Tablet
Drug Interaction
- Antacids
- Antibiotic- Rifampin
Drug Food Interaction
- Dairy products
- Grapefruit juice
Disease Explanation
No disease explanation
FAQ's on Graftide 500mg Tablet
Why has my doctor given me Graftide-M after I have had a kidney transplant?
Graftide-M is an immunosuppressant. Graftide-M has been prescribed to you to help your body accept the donor kidney. It does so by working on the cells of your immune system, which fight with any foreign substance and reject its presence. This helps in making the transplanted organ more acceptable to your body.
What precautions should a female follow while taking Graftide-M?
Do not take Graftide-M if you are pregnant or are planning a pregnancy. There is a high risk of miscarriage (loss of the pregnancy) during the first 3 months of pregnancy. It may even cause birth defects (problems that are present at birth) in the newborn. Therefore, it is advised that you should use two acceptable forms of birth control together for 4 weeks before you start taking Graftide-M, during the treatment and for 6 weeks after you stop taking Graftide-M. It is important to use a second form of birth control along with birth control pills as Graftide-M may decrease the effectiveness of birth control pills.Your doctor will suggest the two birth control methods which suit you the best.
What precautions should a male follow while taking Graftide-M?
It is recommended that either the man or her partner should use reliable contraception during treatment and for 90 days after the treatment. Men should not donate semen during the therapy or for 90 days following discontinuation of Graftide-M.
Do I need any special tests while taking Graftide-M?
Since Graftide-M can affect blood count and affect the kidneys and liver, your doctor will ask you to have a blood test before you start the treatment. Once the treatment starts, your doctor will suggest you to take regular blood tests to check for any changes in the blood. These blood tests will help monitor your response to the medicine and the development of any side effects.
Is Graftide-M a steroid or chemotherapy medicine? Can it cause hair loss?
Graftide-M is neither a steroid nor a chemotherapy medicine. It is an immunosuppressant which means that it acts on your immune system to suppress or weaken it so that your body does not reject the donated organ of another person. Hair loss is a common side effect of Graftide-M.
How long does Graftide-M take to start working?
Graftide-M does not start working immediately and may take about 8 to 12 weeks before you see any benefits. To ensure that your condition does not reappear, you may have to keep taking the medicine for several years.
Can Graftide-M cause cancer?
Graftide-M may increase your chances of certain cancers like skin cancer and lymphoma (cancer of the lymph system). When outside, avoid unnecessary or prolonged exposure to sunlight, wear protective clothing, and apply sunscreen. Call your doctor if you experience a new skin sore or bump, a change in the size or color of a mole, a brown or black skin lesion (sore) with uneven edges or a sore whose one part does not look like the other, skin changes, sores that do not heal. Also, inform the doctor if you experience unexplained fever, tiredness that does not go away, weight loss, or pain or swelling in the neck, groin, or armpits.
My doctor has asked me to stay away from a person who has chicken pox or shingles. Why?
Graftide-M is an immunosuppressant, which means that it decreases the activity of the immune system. Since your immune system is already weak, if you come in contact with a patient of chicken pox or shingles, you may develop it too. This is the reason that your doctor has advised you to be cautious. Therefore, follow your doctor’s advice and contact your doctor immediately if you get chicken pox or shingles as you may require special treatment.
Written By
Rakshita Garg
M.Pharma
Content Updated on
Monday, 22 July, 2024Prescription Required
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