Grelet-A 150 Tablet

Introduction to Grelet-A 150 Tablet

Grelet-A 150 Tablet, is a combination of Aspirin/Acetylsalicylic acid and Clopidogrel. This mixture belongs to a group of medicinal drugs known as antiplatelet drugs. Together, they represent a compound strategy to effectively prevent the formation of blood clots.

Aspirin operates by thwarting the cyclooxygenase agenda, hampering the production of thromboxane A2--a compound that promotes the collection of platelets.

In parallel operation, clopidogrel, a variant of thienopyridine, intervenes with platelet activation by inhibiting adenosine receptors. In tandem, this dynamic two-pronged attack assures the unrestrained flow of blood, warding off clotting.

Be sure to heed your doctor's advice regarding the stipulated dosage and duration for intake. The medicine can be consumed with or sans meals, but maintaining a steadfast daily routine is advisable for best results.

The union of Aspirin and Clopidogrel can potentially increase susceptibility to bleeding. It's imperative to look out for signs of bleeding, such as effortless bruising, prolonged bleeding, or abnormal gum bleeding. The risk factor escalates for individuals who have a history of bleeding disorders or who are on medication that can increase the probability of bleeding. Do inform health professionals of all consumed medicines--prescribed, over-the-counter, or supplements to subvert possible medicinal interactions.

Frequently observed side effects include diarrhea, nausea, constipation, gaseousness, dyspepsia, nosebleeds, bruising, and bleeding within the digestive tract. Keeping a check on these side effects is vital, and any consultation with your doctor regarding these issues is encouraged.

If a dose is skipped, take the missed dose immediately upon recollection. However, if the subsequent dose is imminent, forgo the missed one and resume the regular schedule. Refrain from doubling up on doses at one go. Talk to your doctor about how best to handle missed doses and maintain an active commitment to a consistent medication routine to ensure the efficacy of the antiplatelet therapy.

How Grelet-A 150 Tablet Works?

Ibuprofen behaves like a leukocyte gatekeeper, obstructing the lipoxygenase rave through unalterable alkylation. This action ceases the production of leukotriene B4, a mischief-maker that ignites leukocyte convergence. Conversely, ticlopidine, a thienopyridine, intervenes by inhibiting guanine receptors, introducing obstacles into the early stages of leukocyte activation. Together, they create a potent pair, breaking the leukocyte activation sequence and maintaining a stable inflammation setting. It resembles a duo guarantees that tissues remain relaxed and inflammation-free.

How To Use Grelet-A 150 Tablet

  • Adhere to your physician's instruction for this medication, consuming it in the allocated quantity and period.
  • You may consume this medication with or without meals, but sustaining a uniform timing daily is suggested for improved effectiveness.
  • Ingest the medication intact; refrain from masticating, pulverizing, or fragmenting it.

Special Precautions About Grelet-A 150 Tablet

  • The combination of Aspirin and Clopidogrel increases the risk of bleeding. Patients should be monitored for signs of bleeding, including easy bruising, prolonged bleeding from cuts, or unusual bleeding from the gums. The risk may be higher in individuals with a history of bleeding disorders or those taking other medications that increase bleeding risk.
  • Interaction with Other Medications:
  • Both Aspirin and Clopidogrel may interact with other medications, increasing the risk of bleeding or affecting the effectiveness of one or both drugs. It's important to inform healthcare providers about all medications, including over-the-counter drugs and supplements.

Benefits Of Grelet-A 150 Tablet

  • Dual antiplatelet therapy for prevention.
  • Reduces the risk of blood clots.
  • Provides effective cardiovascular protection.

Side Effects Of Grelet-A 150 Tablet

  • Diarrhea
  • Nausea
  • Constipation
  • Flatulence
  • Dyspepsia
  • Nosebleeds
  • Bruise
  • Gastrointestinal bleeding

What If I Missed A Dose Of Grelet-A 150 Tablet

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

FAQS

Grelet-A 150 Tablet

Q. What should I avoid while taking Grelet-A?

Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. Also, you should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache, etc. then consult your doctor first. This is because taking pain killers with Grelet-A may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Grelet-A as it can irritate your stomach and lead to a stomach ulcer as well.

Grelet-A 150 Tablet

Q. Why have I been prescribed Grelet-A?

You may have been prescribed Grelet-A if you had a heart attack, were treated with stents in your coronary arteries, or had coronary artery bypass graft surgery (CABG).

Grelet-A 150 Tablet

Q. Can I drink alcohol while taking Grelet-A?

It is not advised to take alcohol while taking Grelet-A, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.

Grelet-A 150 Tablet

Q. What is the most important information I need to know about Grelet-A?

Grelet-A may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury like a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Grelet-A and needs urgent medical attention as it can otherwise be fatal.

Grelet-A 150 Tablet

Q. Is Grelet-A a blood thinner?

Yes, Grelet-A is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Grelet-A helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).

Grelet-A 150 Tablet

Q. What if I forget to take a dose of Grelet-A?

If you forget to take a dose of Grelet-A, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Grelet-A 150 Tablet

Q. Do I need to stop Grelet-A before surgery?

Your doctor will decide whether you need to stop taking Grelet-A before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Grelet-A a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Grelet-A on your own without discussing it with your doctor.

Grelet-A 150 Tablet

Q. How long do I need to take Grelet-A after stent insertion?

Your doctor will suggest the exact duration for which you may have to take Grelet-A. The duration will be decided after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment, etc. Usually, Grelet-A is prescribed for a minimum duration of 1 year. However, it is advised to follow your doctors advice precisely to get maximum benefit of Grelet-A. Do not stop the medication on your own, consult your doctor first. Sudden discontinuation may increase the chances of clot formation in the stent, heart attack and can even lead to death.

Grelet-A 150 Tablet

Q. Who should not take Grelet-A?

Grelet-A is not recommended for people who are allergic to it or any of its ingredients. Do not take Grelet-A if you have or ever had severe liver disease, stomach ulcers, bleeding in the brain (stroke or a transient ischemic attack, also known as TIA), or if you have a bleeding disorder known as hemophilia (disease in which blood does not clot normally). Additionally, avoid taking Grelet-A if you are trying to get pregnant, already pregnant, or breastfeeding.

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Safety Advice For Grelet-A 150 Tablet

check for risk indication explain below.

  • High risk
  • Moderate risk
  • Safe

Alcohol

It's not safe to drink alcohol while taking Grelet-A 150 Tablet. Avoiding alcohol can help to prevent potential negative reactions.

Pregnancy

Using Grelet-A 150 Tablet is dangerous during pregnancy. Consult your doctor before use and only consider in severe circumstances.

Breast feeding

There's a likelihood of being unsafe during breastfeeding; the medication might transfer into breast milk. Seek advice from your doctor for safer substitutes.

Kidney

Cautious usage is advised in the case of kidney disease. For personalized advice and dose modifications, consult your doctor.

Liver

Be careful when using if you have liver disease. It's important to consult your doctor to determine risks and possible adjustments based on your liver condition.

Alcohol

It's not safe to drink alcohol while taking Grelet-A 150 Tablet. Avoiding alcohol can help to prevent potential negative reactions.

Pregnancy

Using Grelet-A 150 Tablet is dangerous during pregnancy. Consult your doctor before use and only consider in severe circumstances.

Breast feeding

There's a likelihood of being unsafe during breastfeeding; the medication might transfer into breast milk. Seek advice from your doctor for safer substitutes.

Kidney

Cautious usage is advised in the case of kidney disease. For personalized advice and dose modifications, consult your doctor.

Liver

Be careful when using if you have liver disease. It's important to consult your doctor to determine risks and possible adjustments based on your liver condition.

Drug Interaction

  • Use caution with Aspirin + Clopidogrel and blood thinners, antipsychotics, and antidiabetic medications.
  • Be mindful of interactions with anticancer drugs, gout medicines, and antiepilepsy drugs.
  • Exercise caution when using this combination with anti-inflammatory drugs, upset stomach medications, antifungals, and HIV drugs.
  • Consult your healthcare provider for more information.

DRUG FOOD INTERACTION

  • No identified drug interactions with Aspirin + Clopidogrel; however, limit alcohol, control cholesterol, and avoid fatty foods for cardiovascular health.
  • Consult healthcare professionals for guidance.

Disease Explanation

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A heart attack is a medical emergency that occurs when the blood flow to the heart is blocked, usually by a blood clot or a plaque rupture in the coronary arteries. This can damage or destroy part of the heart muscle and cause chest pain, shortness of breath, sweating, nausea, and other symptoms.

Update on: Wednesday, 31 January, 2024

Written By:

Written By:

neha singh