Leosun 120mg Injection
Introduction to Leosun 120mg Injection
Leosun 120mg Injection is comprised of Artesunate, primarily serving as a medicine for combatting malaria, especially in acute instances. It falls under the artemisinin category of drugs and is recognized in the World Health Organization's Essential Medicines List.
It operates as a prodrug, swiftly morphing into its active entity, dihydroartemisinin (DHA). This conversion produces reactive oxygen species, triggering oxidative stress and inflicting harm on proteins specific to malaria. Furthermore, it obstructs the crucial Plasmodium falciparum exported protein 1 (EXP1), lowering the glutathione quantities of the parasite.
While typically being well accepted, usual side effects entail a decreased heart rate, allergic responses, vertigo, and reduced white blood cell count. In extreme circumstances, instances of kidney failure necessitating dialysis, hemoglobinuria (hemoglobin detected in urine), and jaundice have been noted.
It's suitable for use during pregnancy, specifically in the latter two trimesters, although discretion is recommended in the initial trimester. It's generally harmless for children, with dose modifications needed for ones under 20 kg. Notably, it should be eschewed in newborns when paired with sulfadoxine/pyrimethamine due to probable impacts on bilirubin.
In case of a forgotten dosage, it is critical to seek advice from a medical practitioner for guidance on the suitable follow-up action. The point and extent of the missed dosage will be evaluated to determine the appropriate remedy.
How Leosun 120mg Injection Works?
Penicillin as a warrior fighting against infections. When penicillin enters the scenario, it transforms into penicilloic acid, the true powerhouse. This warrior pair operates in several ways. Firstly, it forms reactive oxygen species, inducing disorder and harming the infection-causing proteins. It also interferes with the microorganism's protein folding, causing it to stumble. Penicillin is like a crafty spy inhibiting a vital protein, PBP, weakening the microorganism's defenses. The warrior pair takes on infections from different directions, making it a powerful force against the disease.
How To Use Leosun 120mg Injection
- Your physician or nurse will supply this medication; please refrain from self-administering.
- Do not consume it by yourself; anticipate instructions from your physician or nurse.
- Believe in your medical expert to dispense the medication; do not venture self-administration.
Special Precautions About Leosun 120mg Injection
- Artesunate is primarily used for the treatment of severe malaria, especially caused by Plasmodium falciparum. It is not typically used for uncomplicated malaria. It is crucial that the diagnosis of severe malaria is confirmed before initiating treatment with Artesunate.
- Regular monitoring of liver function is recommended during Artesunate treatment, especially in patients with preexisting liver conditions. Elevated liver enzymes may occur, and dose adjustments or discontinuation may be necessary.
Benefits Of Leosun 120mg Injection
- Rapid and effective malaria treatment.
- Improves recovery from malaria.
- Demonstrates high antimalarial potency.
Side Effects Of Leosun 120mg Injection
- Headache
- Dizziness
- Vomiting
- Abdominal pain
- Cough
- Decreased white blood cell count
- Taste change
- Fever
What If I Missed A Dose Of Leosun 120mg Injection
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For information purposes only. Consult a doctor before taking any medicines.
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Safety Advice For Leosun 120mg Injection
check for risk indication explain below.
- High risk
- Moderate risk
- Safe
Alcohol
The combination of Leosun 120mg Injection and alcohol may not be safe. Please consult your doctor for personalized advice regarding alcohol consumption while using this drug.
Pregnancy
It's potentially unsafe to use Leosun 120mg Injection during pregnancy. Based on animal studies, it could harm your developing baby. Seek advice from your doctor to weigh the risks and benefits ahead of using this medication.
Breast feeding
The use of Leosun 120mg Injection is likely safe during breastfeeding. According to limited human data, the risk to the baby appears to be insignificant. Please follow your doctor's instructions and advice to ensure a risk-free breastfeeding experience.
Kidney
Only limited data is accessible regarding the usage of Leosun 120mg Injection for patients with kidney disease. Please seek personalized advice from your doctor, and ask about potential adjustments based on your kidney condition.
Liver
Limited data is available regarding the application of Leosun 120mg Injection in patients afflicted with liver disease. Request personalized guidance from your doctor, including potential modifications considering your liver condition.
Alcohol
The combination of Leosun 120mg Injection and alcohol may not be safe. Please consult your doctor for personalized advice regarding alcohol consumption while using this drug.
Pregnancy
It's potentially unsafe to use Leosun 120mg Injection during pregnancy. Based on animal studies, it could harm your developing baby. Seek advice from your doctor to weigh the risks and benefits ahead of using this medication.
Breast feeding
The use of Leosun 120mg Injection is likely safe during breastfeeding. According to limited human data, the risk to the baby appears to be insignificant. Please follow your doctor's instructions and advice to ensure a risk-free breastfeeding experience.
Kidney
Only limited data is accessible regarding the usage of Leosun 120mg Injection for patients with kidney disease. Please seek personalized advice from your doctor, and ask about potential adjustments based on your kidney condition.
Liver
Limited data is available regarding the application of Leosun 120mg Injection in patients afflicted with liver disease. Request personalized guidance from your doctor, including potential modifications considering your liver condition.
Drug Interaction
- Consult a healthcare provider for an accurate interpretation of interactions with Artesunate; seek immediate help if experiencing adverse effects.
- Note that the absence of interaction does not guarantee any interactions.
- Exercise caution with drugs like Acetophenazine, Alimemazine, and Artemether, which may increase QTc prolongation.
- Ambroxol can elevate the risk of methemoglobinemia when combined with Artesunate.
- Stay vigilant with Articaine, as its combination with Artesunate may also heighten the risk of methemoglobinemia.
DRUG FOOD INTERACTION
- No interactions were identified between Artesunate and food; Consult a healthcare provider for accurate information and potential drug-related concerns.
- Consult your healthcare provider for more information.
Disease Explanation
Malaria is a disease caused by a parasite that infects some types of mosquitoes. When an infected mosquito bites a person, it can transmit the parasite to their blood. Malaria can cause fever, headache, chills, and sometimes severe complications or death. Malaria can be prevented by avoiding mosquito bites and taking medicines.
Update on: Wednesday, 31 January, 2024
Written By:
neha singh
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