Leptomate does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in blood (hyperammonemia). Increased levels of ammonia in blood can be dangerous and may cause difficulty in thinking, remembering information or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, Leptomate alone can cause hyperammonemia.

The dose and duration of this medicine will depend on your doctor’s advice. Leptomate does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.

Serious side effects of Leptomate are rare. The serious effects of Leptomate may include glaucoma (difficulty in seeing, eye pain and blurred vision), kidney stones (sharp pain in your sides or lower back) and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Leptomate could be suicidal thoughts and insufficient sweating (some children taking Leptomate may not sweat enough in hot weather, causing their body temperatures to rise).

Yes, Leptomate is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraine.

It could be due to Leptomate because Leptomate commonly causes weight loss probably due to decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.

Leptomate is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.