O Fair Plus Cream is employed for the treatment of melasma, a skin condition characterized by the presence of dark patches. This formulation, designed for external use only, works synergistically to promote rapid skin renewal, aiding in the restoration of skin cells. Beyond addressing melasma, it provides relief from common skin issues like redness, swelling, and itching, ultimately contributing to an improved skin appearance and texture.

The combination's efficacy lies in synergistically addressing melasma and enhancing skin health. Hydroquinone acts by inhibiting melanin production, and lightening dark patches. Mometasone, a corticosteroid, alleviates inflammation, redness, and swelling, while Tretinoin promotes skin renewal by encouraging the turnover of skin cells.

Before application, the affected area should be cleaned and dried as directed on the label. After applying, hands should be washed, unless they are part of the affected area.

Patients are advised to notify their doctor of any known allergies before using the medication. A patch test should be performed before widespread application to check for skin sensitivity. Due to increased skin sensitivity caused by the combination, sun exposure should be avoided, and protective measures such as sunscreen and clothing should be employed.