Similar Medicine Of Pipzo 4.5gm Injection
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Pipzo 4.5gm Injection is a broad-spectrum antibiotic used to treat severe bacterial infections, including pneumonia, urinary tract infections (UTIs), sepsis, and intra-abdominal infections. It contains Piperacillin (4g), a penicillin-type antibiotic, and Tazobactam (0.5g), a beta-lactamase inhibitor, which together help kill bacteria and prevent antibiotic resistance.
How Pipzo 4.5gm Injection works
Piperacillin is a penicillin group's antibiotic and inhibits the synthesis of the bacterial cell wall, causing bacterial death. Tazobactam inhibits the production of beta-lactamase enzymes by bacteria to resist antibiotics and enhance the activity of Piperacillin.
How To Use Pipzo 4.5gm Injection
- Dosage: Adults: 4.5g every 6-8 hours, depending on infection severity. Children: Dose adjusted based on weight.
- Administration: Pipzo 4.5gm Injection is given intravenously (IV) by a doctor or nurse. Do not self-administer.
- Duration: 5-14 days, depending on the infection. Complete the full course to prevent resistance.
Special Precautions About Pipzo 4.5gm Injection
- Not recommended in severe kidney disease—dose adjustments may be needed.
- Use with caution in penicillin-allergic patients.
- Pipzo 4.5gm Injection may cause diarrhea due to gut bacteria imbalance.
- May reduce potassium levels—patients with electrolyte imbalance should be monitored.
Benefits Of Pipzo 4.5gm Injection
- It is a broad-spectrum antibiotic.
- Pipzo 4.5gm Injection is used for treatment of severe bacterial infection. eg; Urinary tract infection, Pneumonia, Sepsis, Skin infection and Intra-abdominal infection.
- Effective against antibiotic resistant bacteria.
Side Effects Of Pipzo 4.5gm Injection
- Common Side Effects: Nausea, diarrhea, headache, rash, vomiting.
- Serious Side Effects: Severe allergic reactions (swelling, difficulty breathing), kidney damage, abnormal liver function.
What If I Missed A Dose Of Pipzo 4.5gm Injection
- Since it is administered in a hospital, missing a dose is unlikely.
- Inform the doctor immediately if a dose is missed.
Health And Lifestyle
Drug Interaction
- Blood Thinners (e.g., Warfarin, Heparin) – May increase bleeding risk.
- Diuretics (e.g., Furosemide) – May cause electrolyte imbalance.
- Methotrexate (used in cancer/arthritis) – May increase toxicity.
- Probenecid (used in gout) – May increase antibiotic levels in the blood.
Drug Food Interaction
- N/A
Disease Explanation

Pneumonia – A bacterial lung infection causing fever, cough, and breathing difficulty. Sepsis – A life-threatening condition where bacteria enter the bloodstream, causing severe inflammation. Complicated UTIs – Severe urinary tract infections that spread to the kidneys and require hospitalization.
Safety Advice for Pipzo 4.5gm Injection
- High risk
- Moderate risk
- Safe
Prolonged use in patient with liver impairment can cause Jaundice.
Patient With kidney function impairments, should use with caution.
Usually does not cause any harmful side effects but in some patient, it can cause nausea and Vomiting.
Pipzo 4.5gm Injection can alter the physical and mental fatigue so, affects driving ability.
Usually safe to use during pregnancy.
Safe to use during breast feeding.
Tips of Pipzo 4.5gm Injection
- Complete the full antibiotic course, even if you feel better.
- Inform your doctor if you have a penicillin allergy before starting treatment.
- Do not mix with other IV drugs unless prescribed.
FactBox of Pipzo 4.5gm Injection
- Manufacturer: Cipla Ltd
- Composition: Piperacillin (4g) + Tazobactam (0.5g)
- Class: Beta-lactam Antibiotic + Beta-lactamase Inhibitor
- Uses: Treats severe bacterial infections like pneumonia, UTIs, sepsis
- Prescription: Required
- Storage: Store below 25°C, away from moisture
Storage of Pipzo 4.5gm Injection
- Store in a cool, dry place below 25°C.
- Keep out of reach of children.
- Protect from light and moisture.
Dosage of Pipzo 4.5gm Injection
- Adults: 4.5g every 6-8 hours, as prescribed.
- Children: Dose adjusted based on weight.
Synopsis of Pipzo 4.5gm Injection
Pipzo 4.5gm Injection is a broad-spectrum antibiotic that effectively treats severe bacterial infections like pneumonia, sepsis, and complicated UTIs. It is administered intravenously in hospitals and provides quick and effective bacterial control.
FAQ's on Pipzo 4.5gm Injection
Can the use of Pipzo cause contraceptive failure?
Can Pipzo cause an allergic reaction?
Is it safe to use Pipzo?
Can the use of Pipzo cause diarrhea?
What are the instructions for the storage and disposal of Pipzo?
Are there any specific cautions associated with the use of Pipzo?
How is Pipzo administered?
Can I take a higher than the recommended dose of Pipzo?
What is Pipzo?
How long does Pipzo take to work?
Can Pipzo be used for urinary tract infections (UTIs)?
Does Pipzo treat pneumonia?
Can Pipzo cause allergic reactions?
Is Pipzo safe for kidney patients?
Can I take Pipzo at home?
Does Pipzo affect liver function?
Is Pipzo effective against multi-drug resistant bacteria?
Can Pipzo be used in pregnancy?
Does Pipzo interact with blood thinners?
Written By
Salony Priya
MBA in pharmaceutical management
Content Updated on
Saturday, 28 June, 2025