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Introduction to Pirfenex 200mg Tablet 15s
These medicines are used to treat idiopathic pulmonary fibrosis (IPF); which is a chronic and progressive lung disease. It slows down scarring, improves lung functioning and reduces fibrosis and inflammation. This medicine manages IPF by exhibiting anti-inflammatory therapy.
Safety Advice for Pirfenex 200mg Tablet 15s
- High risk
- Moderate risk
- Safe
It should be used cautiously in patients suffering liver disease; dosage adjustment and regular monitoring of liver function is necessary.
It should be used cautiously in patients suffering kidney disease; dosage adjustment may be necessary.
Limit alcohol intake as it can exacerbate liver toxicity.
Avoid driving as this drug may induce side effects like fatigue or dizziness.
There is no sufficient information regarding the safety of this drug to the developing baby; doctor's consultation is required before using it.
There is no sufficient information regarding the safety of this drug to the developing baby; doctor's consultation is required before using it.
How Pirfenex 200mg Tablet 15s works
Active ingredients present in this medicine; Pirfenidone shows its activity by inhibiting the synthesis of transforming growth factor-beta and other pro-inflammatory cytokines. It retards lung fibrosis development by reducing collagen production and fibroblast proliferation. Working in this manner helps slow down lung scavenging and preserves the proper functioning of the lungs.
How To Use Pirfenex 200mg Tablet 15s
- Take the medicine under the healthcare professional's supervision.
- Dose will be increased gradually to reduce potential side effects.
- Swallow the dose as a whole with water, and take it after having a meal.
- It is important to be consistent and keep adhered to the prescribed regimen.
Special Precautions About Pirfenex 200mg Tablet 15s
- It should be used cautiously among patients having a medical history of photosensitivity reactions.
- Liver functions are required to be tested regularly.
- Avoid exposure to direct sunlight; use sunscreen before going out in sun and wear protective clothing
Benefits Of Pirfenex 200mg Tablet 15s
- Slow down the progression of lung scarring in IPF.
- Helps preserve lung function.
- Reduces symptoms such as cough and breathlessness.
Side Effects Of Pirfenex 200mg Tablet 15s
- nausea
- loss of appetite
- rash
- diarrhea
- fatigue
- gastrointestinal bleeding
- liver dysfunction
- severe photosensitivity
Similar Medicine Of Pirfenex 200mg Tablet 15s
What If I Missed A Dose Of Pirfenex 200mg Tablet 15s
- Don't skip any drug of the dose. If forgotten, take it once remembered.
- If the next dose time is near, skip the missed one.
- Avoid doubling to compensate. Follow this routine for safe and effective usage.
- For guidance on managing missed doses, consult your healthcare provider, ensuring proper adherence to the prescribed regimen.
Health And Lifestyle
To manage this health condition, apart from taking antifibrotic medicines timely, do pulmonary rehabilitation practice, stop smoking, take oxygen therapy. Regular monitoring of lungs is necessary during treatment with this medicine.
Drug Interaction
- Strong CYP1A2 Inducers (e.g., Rifampicin)
- CYP1A2 Inhibitors (e.g., Ciprofloxacin)
Drug Food Interaction
- Grapefruit Juice
- High-Fat Meals
Disease Explanation
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by scarring (fibrosis) of the lung tissues. Fibrosis reduces lung function, causes dry cough to persist and makes breathing difficult.
FAQ's on Pirfenex 200mg Tablet 15s
What is idiopathic lung disease?
Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring (fibrosis) of the lungs for an unknown reason. Over time, the scarring gets worse and it becomes hard to take in a deep breath and the lungs cannot take in enough oxygen.
What are the side effects of Pirfenex Tablet?
Most common side effects of Pirfenex Tablet include skin sensitivity to sunlight, nausea, tiredness, diarrhea, indigestion or upset stomach, loss of appetite, and headache. Other common side effects include infections of the throat or the airways, bladder infections, weight loss, difficulty sleeping, dizziness, sleepiness, changes in taste, hot flushes, shortness of breath, and cough. Additionally, one may experience stomach problems such as acid reflux, vomiting, bloating, abdominal pain and discomfort, heart burn, constipation, skin problems such as itchy skin, skin redness or red skin, dry skin, skin rash, muscle pain, aching joints/joint pains, weakness, chest pain, and sunburn. It is possible that after using Pirfenex Tablet blood tests may show increased levels of liver enzymes.
What is the first sign of pulmonary fibrosis?
Shortness of breath (dyspnea) is the most commonly associated symptom of pulmonary fibrosis. It begins with shortness of breath during physical exertion but as the disease progresses, patients will find they suffer shortness of breath even while resting.
What is lung fibrosis?
Pulmonary fibrosis is a lung disease that occurs when lung tissue becomes damaged and scarred. This thickened, stiff tissue makes it more difficult for your lungs to work properly. As pulmonary fibrosis worsens, you become progressively more short of breath.
Is Pulmoclear tablet an antibiotic?
Pulmoclear Tablet is a combination of two mucolytic medicines: Acebrophylline and Acetylcysteine. It thins and loosens mucus (phlegm) making it easier to cough out.
What causes fibrosis?
There are a number of known causes of pulmonary fibrosis as well as unknown causes, called idiopathic. Exposure to toxins like asbestos, or coal dust or silica (including workers in the coal mining and sandblasting industry) can lead to pulmonary fibrosis.
Is Pirfenex Tablet a steroid?
No, Pirfenex Tablet is not a steroid. It belongs to pyridines group of medicines. It is used to treat idiopathic pulmonary fibrosis (IPF) in adults. In IPF, the tissues of the lungs get scarred and swell with time, which creates problem in breathing. This medicine helps reduce these effects to make you breathe better.
Can fibrosis be cured?
Is there a cure for pulmonary fibrosis? No cure is currently available for pulmonary fibrosis, but treatments can help reduce symptoms, with new therapies under development. Immunosuppressant medications can also be prescribed to treat pulmonary fibrosis. In severe cases, lung transplant may be necessary.
How much is pirfenidone cost?
Mean all-cause outpatient service costs per patient per month were $581 for pirfenidone and $1042 for nintedanib (P = . 553). Mean respiratory-related inpatient costs were $581 for pirfenidone and $833 for nintedanib (P = . 041).
What is the survival rate of pulmonary fibrosis?
The median survival of patients with pulmonary fibrosis is 2-3 years, yet some people live much longer. The factors which can be held responsible for shortened survival are older age, smoking history, and lower body mass index. The other factors can be more severe extent of disease both radiologically and physical impairment, and the development of other lung complications or conditions.
What is the use of 200 tablet?
OF 200 Tablet is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.
What tab Pirfenex is used for?
Pirfenex Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better.
Why is it important to continue treatment with Pirfenex Tablet?
It is important to control the progression of the disease by preserving your lung function which cannot be restored, once lost. Hence, it is highly recommended to start and continue the treatment with Pirfenex Tablet as prescribed by your doctor. Doing so can help preserve the existing lung function.
What should I avoid while taking Pirfenex Tablet?
You should restrict sun exposure, while taking Pirfenex Tablet. Wear sunblock daily and cover your arms, legs, and head to reduce exposure to sunlight. Along with that, avoid smoking as it decreases the effect of Pirfenex Tablet.
Is pirfenidone an antibiotic?
However, before assessing the effect of pirfenidone during TB treatment, it was imperative to confirm that it possessed no antibacterial activity and did not adversely interact with the antibacterial properties of the 2 cornerstone drugs of TB treatment, isoniazid and rifampin.
Can you survive pulmonary fibrosis?
Idiopathic pulmonary fibrosis (IPF) portends a poor prognosis. With regard to idiopathic pulmonary fibrosis life expectancy, the estimated mean survival is 2-5 years from the time of diagnosis. Estimated mortality rates are 64.3 deaths per million in men and 58.4 deaths per million in women.
How do you take pirfenidone?
Take this medication by mouth with food as directed by your doctor, usually 3 times a day. Taking pirfenidone with food may help decrease dizziness and nausea. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose.
How do I know that Pirfenex Tablet is right for me?
Only you and your doctor can decide if Pirfenex Tablet is right for you. The doctor will only prescribe Pirfenex Tablet after assessing your condition. Based on your response to treatment and tolerability, you should continue the medicine.
If my disease is stable can I stop Pirfenex Tablet?
Idiopathic pulmonary fibrosis is a progressive disease though its progression is unpredictable. Do not stop the medication without consulting the doctor. Continue taking Pirfenex Tablet to slow down the progression of the disease.
What monitoring will I need during treatment with Pirfenex Tablet?
Your doctor will check your liver function before starting treatment with Pirfenex Tablet. This test will be repeated monthly for the first 6 months and then it will be done after every three months. In addition to that, your doctor will also monitor your lung function periodically in order to see the response to Pirfenex Tablet.
Does pirfenidone really work?
Conclusion. Randomised controlled trials have demonstrated that pirfenidone significantly slows disease progression and reduces mortality in patients with IPF [3, 4].
Written By
Rakshita Garg
M.Pharma
Content Updated on
Saturday, 27 July, 2024Prescription Required
Pirfenex 200mg Tablet 15s
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